1. Introduction to Special Issue: Targeted Toxins for Glioma Therapy

   • Raj K. Puri

   Editorial Introduction Pages: 1 - 2

2. Transferrin Receptor Ligand-Targeted Toxin Conjugate (Tf-CRM107) for Therapy of Malignant Gliomas

   • Michael Weaver
   • Douglas W. Laske

   OriginalPaper Pages: 3 - 14

3. Interleukin-4-Pseudomonas Exotoxin Chimeric Fusion Protein for Malignant Glioma Therapy

   • Mariko Kawakami
   • Koji Kawakami
   • Raj K. Puri

   OriginalPaper Pages: 15 - 25

4. Progress Report of a Phase I Study of the Intracerebral Microinfusion of a Recombinant Chimeric Protein Composed of Transforming Growth Factor (TGF)-α and a Mutated form of the Pseudomonas Exotoxin Termed PE-38 (TP-38) for the Treatment of Malignant Brain Tumors

   • John H. Sampson
   • Gamal Akabani
   • Ira Pastan

   OriginalPaper Pages: 27 - 35

5. Interleukin-13 Receptor-Directed Cytotoxin for Malignant Glioma Therapy: From Bench to Bedside

   • Syed R. Husain
   • Raj K. Puri

   OriginalPaper Pages: 37 - 48

6. BR96–DOX Immunoconjugate Targeting of Chemotherapy in Brain Tumor Models

   • Leslie L. Muldoon
   • Edward A. Neuwelt

   OriginalPaper Pages: 49 - 62

7. Targeting the Over-Expressed Urokinase-Type Plasminogen Activator Receptor on Glioblastoma Multiforme

   • Edward Rustamzadeh
   • Chunbin Li
   • Daniel A. Vallera

   OriginalPaper Pages: 63 - 75

8. Combination Fusion Protein Therapy of Refractory Brain Tumors: Demonstration of Efficacy in Cell Culture

   • Tie Fu Liu
   • Kimberly A. Cohen
   • Arthur E. Frankel

   OriginalPaper Pages: 77 - 85

9. Neuro-Oncology International Calendar of Events

   Events Pages: 87 - 88

10. Instruction for Authors

    Instructions for Authors Pages: 89 - 93