1. Preface

   • Richard C. Wiggins

   Preface Pages: 219 - 220

2. Pathophysiology of Hepatic Encephalopathy: A New Look at Ammonia

   • Roger F. Butterworth

   OriginalPaper Pages: 221 - 227

3. Cerebral Blood Flow in Hyperammonemia: Heterogeneity and Starling Forces in Capillaries

   • Fin Stolze Larsen

   OriginalPaper Pages: 229 - 235

4. Effects of Hyperammonemia and Liver Failure on Glutamatergic Neurotransmission

   • Pilar Monfort
   • María-Dolores Muñoz
   • Vicente Felipo

   OriginalPaper Pages: 237 - 250

5. Increased Extracellular Brain Glutamate in Acute Liver Failure: Decreased Uptake or Increased Release?

   • Christopher Rose

   OriginalPaper Pages: 251 - 261

6. Reduced Expression of Astrocytic Glycine Transporter (Glyt-1) in Acute Liver Failure

   • Claudia Zwingmann
   • Paul Desjardins
   • Roger F. Butterworth

   OriginalPaper Pages: 263 - 273

7. Ammonia, the GABA Neurotransmitter System, and Hepatic Encephalopathy

   • E. Anthony Jones

   OriginalPaper Pages: 275 - 281

8. The Role of Inhibitory Amino Acidergic Neurotransmission in Hepatic Encephalopathy: A Critical Overview

   • Jan Albrecht
   • Magdalena Zielińska

   OriginalPaper Pages: 283 - 294

9. Altered Modulation of Soluble Guanylate Cyclase by Nitric Oxide in Patients with Liver Disease

   • R. Corbalán
   • C. Montoliu
   • V. Felipo

   OriginalPaper Pages: 295 - 301

10. Nitric Oxide in Patients with Cirrhosis and Bacterial Infections

    • José Such
    • Rubén Francés
    • Miguel Pérez-Mateo

    OriginalPaper Pages: 303 - 309

11. Nitric Oxide and Portal Hypertension

    • Juan González-Abraldes
    • Juan Carlos García-Pagán
    • Jaime Bosch

    OriginalPaper Pages: 311 - 324

12. Nitric Oxide in Liver Inflammation and Regeneration

    • Paloma Martin-Sanz
    • Sonsoles Hortelano
    • Lisardo Boscá

    OriginalPaper Pages: 325 - 334

13. Pathogenesis and Pathophysiology of Citrin (a Mitochondrial Aspartate Glutamate Carrier) Deficiency

    • Takeyori Saheki
    • Keiko Kobayashi
    • Meng Xian Li

    OriginalPaper Pages: 335 - 346

14. Central Nervous System Alterations in Liver Cirrhosis: The Role of Portal-Systemic Shunt and Portal Hypoperfusion

    • Franco Del Piccolo
    • David Sacerdoti
    • Angelo Gatta

    OriginalPaper Pages: 347 - 358

15. Hyperammonemia in Carnitine-Deficient Adult JVS Mice Caused by Starvation

    • Meng Xian Li
    • Keiko Kobayashi
    • Takeyori Saheki

    OriginalPaper Pages: 359 - 366

16. Valproate-Induced Hyperammonemic Encephalopathy

    • Alberto Verrotti
    • Daniela Trotta
    • Francesco Chiarelli

    OriginalPaper Pages: 367 - 373

17. Manganese Neurotoxicity: An Update of Pathophysiologic Mechanisms

    • Louise Normandin
    • Alan S. Hazell

    OriginalPaper Pages: 375 - 387

18. Prevention of Ammonia and Glutamate Neurotoxicity by Carnitine: Molecular Mechanisms

    • Marta Llansola
    • Slaven Erceg
    • Vicente Felipo

    OriginalPaper Pages: 389 - 397

19. Clinical Significance of Basal Ganglia Alterations at Brain MRI and ¹H MRS in Cirrhosis and Role in the Pathogenesis of Hepatic Encephalopathy

    • Laurent Spahr
    • Pierre R. Burkhard
    • Antoine Hadengue

    OriginalPaper Pages: 399 - 413

20. ¹H Magnetic Resonance in the Study of Hepatic Encephalopathy in Humans

    • Juan Córdoba
    • Francesc Sanpedro
    • Alex Rovira

    OriginalPaper Pages: 415 - 429

21. Positron Emission Tomography in the Study of Hepatic Encephalopathy

    • Alan H. Lockwood

    OriginalPaper Pages: 431 - 435

22. Hypothermia for the Management of Intracranial Hypertension in Acute Liver Failure

    • Rajiv Jalan
    • Nathan A. Davies
    • Steven W. M. Olde Damink

    OriginalPaper Pages: 437 - 444

23. Mild Hypothermia in the Prevention of Brain Edema in Acute Liver Failure: Mechanisms and Clinical Prospects

    • Nicolas Chatauret
    • Christopher Rose
    • Roger F. Butterworth

    OriginalPaper Pages: 445 - 451

24. Clinical Efficacy of L-Ornithine–L-Aspartate in the Management of Hepatic Encephalopathy

    • G. Kircheis
    • M. Wettstein
    • D. Häussinger

    OriginalPaper Pages: 453 - 462

25. Improvement in Central Nervous System Functions During Treatment of Liver Failure with Albumin Dialysis MARS—A Review of Clinical, Biochemical, and Electrophysiological Data

    • S. Mitzner
    • J. Loock
    • R. Schmidt

    OriginalPaper Pages: 463 - 475

26. Concept for Modular Extracorporeal Liver Support for the Treatment of Acute Hepatic Failure

    • I. M. Sauer
    • P. Neuhaus
    • J. C. Gerlach

    OriginalPaper Pages: 477 - 484

27. Bioartificial Liver Support Anno 2001

    • Robert A. F. M. Chamuleau

    OriginalPaper Pages: 485 - 491

28. Author Index to Volume 17 (2002)

    Authors Index Pages: 493 - 494

29. Subject Index to Volume 17 (2002)

    Subject Index Pages: 495 - 497