1. Preface

   • Xianglin Shi
   • Vince Castranova
   • Val Vallyathan

   BriefCommunication Pages: 1 - 1

2. Conference overview: Molecular mechanisms of metal toxicity and carcinogenesis

   • Jacquelyn J. Bower
   • Stephen S. Leonard
   • Xianglin Shi

   OriginalPaper Pages: 3 - 15

3. Effect of stainless steel manual metal arc welding fume on free radical production, DNA damage, and apoptosis induction

   • James M. Antonini
   • Stephen S. Leonard
   • Michael D. Taylor

   OriginalPaper Pages: 17 - 23

4. ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells

   • Jingxia Li
   • Qiangsong Tong
   • Chuanshu Huang

   OriginalPaper Pages: 25 - 33

5. Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression

   • Weiming Ouyang
   • Jingxia Li
   • Chuanshu Huang

   OriginalPaper Pages: 35 - 43

6. Carcinogenic effect of nickel compounds

   • Haitian Lu
   • Xianglin Shi
   • Chuanshu Huang

   OriginalPaper Pages: 45 - 67

7. Involvement of the p38 MAP kinase in Cr(VI)-induced growth arrest and apoptosis

   • Timothy P. Wakeman
   • Dorota Wyczechowska
   • Bo Xu

   OriginalPaper Pages: 69 - 73

8. Human lung cell growth is not stimulated by lead ions after lead chromate-induced genotoxicity

   • Sandra S. Wise
   • Amie L. Holmes
   • John Pierce Wise Sr.

   OriginalPaper Pages: 75 - 84

9. Nucleotide excision repair functions in the removal of chromium-induced DNA damage in mammalian cells

   • Travis J. O'Brien
   • Bradford R. Brooks
   • Steven R. Patierno

   OriginalPaper Pages: 85 - 95

10. Leukemic transformation of hematopoietic cells in mice internally exposed to depleted uranium

    • Alexandra C. Miller
    • Catherine Bonait-Pellie
    • Paul D. Lison

    OriginalPaper Pages: 97 - 104

11. Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes

    • Wei Ding
    • Laurie G. Hudson
    • Ke Jian Liu

    OriginalPaper Pages: 105 - 112

12. Oxidation and methylation status determine the effects of arsenic on the mitotic apparatus

    • A. D. Kligerman
    • C. L. Doerr
    • A. H. Tennant

    OriginalPaper Pages: 113 - 121

13. Sodium arsenite-induced inhibition of eukaryotic translation initiation factor 4E (eIF4E) results in cytotoxicity and cell death

    • Sreekumar Othumpangat
    • Michael Kashon
    • Pius Joseph

    OriginalPaper Pages: 123 - 131

14. Inhibition of core histones acetylation by carcinogenic nickel(II)

    • Filip Golebiowski
    • Kazimierz S. Kasprzak

    OriginalPaper Pages: 133 - 139

15. Expression of copper-responsive genes in HepG2 cells

    • Min Ok Song
    • Jonathan H. Freedman

    OriginalPaper Pages: 141 - 147

16. Differential impact of ionic and coordinate covalent chromium (Cr)-DNA binding on DNA replication

    • Jamie L. Fornsaglio
    • Travis J. O'Brien
    • Steven R. Patierno

    OriginalPaper Pages: 149 - 155

17. Soluble nickel interferes with cellular iron homeostasis

    • Todd Davidson
    • Haobin Chen
    • Max Costa

    OriginalPaper Pages: 157 - 162

18. Deficiency in Ikkβ gene enhances arsenic-induced gadd45α expression

    • Yadong Zhang
    • Yongju Lu
    • Fei Chen

    OriginalPaper Pages: 163 - 168

19. Resistance to apoptosis, increased growth potential, and altered gene expression in cells that survived genotoxic hexavalent chromium [Cr(VI)] exposure

    • Daryl E. Pritchard
    • Susan Ceryak
    • Steven R. Patierno

    OriginalPaper Pages: 169 - 181

20. Index to Volume 279

    • Editorial Boards

    BriefCommunication Pages: 183 - 184

21. Instructions for Authors

    • Naranjan S. Dhalla

    BriefCommunication Pages: 185 - 185