1. Delay differential equations based models in NONMEM

   • Xiaoyu Yan
   • Robert Bauer
   • Wojciech Krzyzanski

   Tutorial 23 July 2021 Pages: 763 - 802

   

2. Optimal control for colistin dosage selection

   • Aline Vidal Lacerda Gontijo
   • André V. G. Cavalieri

   Original Paper 22 June 2021 Pages: 803 - 813

   

3. Linking categorical models for prediction of pleasantness score using individual predictions of sweetness and creaminess: An advancement of categorical modeling

   • Jennifer Leohr
   • Maria C. Kjellsson

   Original Paper Open access 01 July 2021 Pages: 815 - 823

   

4. Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 1. THR-149

   • Marc Vanhove
   • Bernard Noppen
   • Alan W. Stitt

   Original Paper Open access 23 July 2021 Pages: 825 - 836

   

5. Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 2. THR-687

   • Marc Vanhove
   • Jean-Marc Wagner
   • Alan W. Stitt

   Original Paper Open access 23 July 2021 Pages: 837 - 849

   

6. Evaluation of covariate effects using variance-based global sensitivity analysis in pharmacometrics

   • Takayuki Katsube
   • Toshihiro Wajima

   Original Paper 04 August 2021 Pages: 851 - 860

   

7. Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases

   • Peter Bloomingdale
   • Suruchi Bakshi
   • Nitin Mehrotra

   Original Paper Open access 10 August 2021 Pages: 861 - 871

   

8. What should patients do if they miss a dose of medication? A theoretical approach

   • Elijah D. Counterman
   • Sean D. Lawley

   Original Paper 10 September 2021 Pages: 873 - 892

   

9. A Bayesian population physiologically based pharmacokinetic absorption modeling approach to support generic drug development: application to bupropion hydrochloride oral dosage forms

   • Nan-Hung Hsieh
   • Frédéric Y. Bois
   • Weihsueh A. Chiu

   Original Paper 22 September 2021 Pages: 893 - 908

   

10. Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study

    • Maxime Le Merdy
    • Jim Mullin
    • Viera Lukacova

    Original Paper Open access 26 September 2021 Pages: 909 - 922