1. Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist

   • Kayode Ogungbenro
   • Sharon Hulme
   • James Galea

   Original Paper 18 October 2015 Pages: 1 - 12

   

2. Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment

   • Sophie Peigné
   • François Bouzom
   • Marylore Chenel

   Original Paper 12 November 2015 Pages: 13 - 27

   

3. Model-based approaches for ivabradine development in paediatric population, part II: PK and PK/PD assessment

   • Sophie Peigné
   • Sylvain Fouliard
   • Marylore Chenel

   Original Paper 14 November 2015 Pages: 29 - 43

   

4. Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

   • Chuanpu Hu
   • Honghui Zhou

   Original Paper 09 November 2015 Pages: 45 - 54

   

5. Erratum to: Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

   • Chuanpu Hu
   • Honghui Zhou

   Erratum 23 November 2015 Pages: 55 - 55

6. Application of a hazard-based visual predictive check to evaluate parametric hazard models

   • Yeamin Huh
   • Matthew M. Hutmacher

   Original Paper 13 November 2015 Pages: 57 - 71

   

7. Population pharmacokinetics of ramosetron

   • Seong Heon Lee
   • Soo Young Cho
   • Seongwook Jeong

   Original Paper 11 November 2015 Pages: 73 - 83

   

8. Stochastic nonlinear mixed effects: a metformin case study

   • Brett Matzuka
   • Jason Chittenden
   • Hien Tran

   Original Paper 19 November 2015 Pages: 85 - 98

   

9. A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation

   • Ayman Akil
   • Robert R. Bies
   • Constantine G. Lyketsos

   Original Paper Open access 26 November 2015 Pages: 99 - 109

   

10. What do we mean by identifiability in mixed effects models?

    • Marc Lavielle
    • Leon Aarons

    Original Paper 10 December 2015 Pages: 111 - 122