1. A semi-mechanistic model of bone mineral density and bone turnover based on a circular model of bone remodeling

   • Erno van Schaick
   • Jenny Zheng
   • Philippe Jacqmin

   Original Paper 30 June 2015 Pages: 315 - 332

   

2. Using early biomarker data to predict long-term bone mineral density: application of semi-mechanistic bone cycle model on denosumab data

   • Jenny Zheng
   • Erno van Schaick
   • Juan Jose Perez Ruixo

   Original Paper 30 June 2015 Pages: 333 - 347

   

3. Incorporation of stochastic variability in mechanistic population pharmacokinetic models: handling the physiological constraints using normal transformations

   • Nikolaos Tsamandouras
   • Thierry Wendling
   • Leon Aarons

   Original Paper 26 May 2015 Pages: 349 - 373

   

4. Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model

   • Michael A. Lyons
   • Anne J. Lenaerts

   Original Paper 31 May 2015 Pages: 375 - 389

   

5. Quantitative characterization of circadian rhythm of pulmonary function in asthmatic patients treated with inhaled corticosteroids

   • Di Zhou
   • Hongshan Li
   • Liang Zhao

   Original Paper 23 June 2015 Pages: 391 - 399

   

6. Pharmacokinetics and pharmacodynamics of 3,3′-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes

   • Tien-Yuan Wu
   • Ying Huang
   • Ah-Ng Tony Kong

   Original Paper 03 July 2015 Pages: 401 - 408

   

7. A PBPK model describing a xenobiotic with a short PK event scale

   • Xiaofeng Wang
   • Brian E. Davies

   Original Paper 09 July 2015 Pages: 409 - 416

   

8. The method of averaging applied to pharmacokinetic/pharmacodynamic indirect response models

   • Adrian Dunne
   • Willem de Winter
   • Xavier Woot de Trixhe

   Original Paper 05 July 2015 Pages: 417 - 426