A “middle-out” approach to human pharmacokinetic predictions for OATP substrates using physiologically-based pharmacokinetic modeling Rui LiHugh A. BartonTristan S. Maurer Original Paper 10 April 2014 Pages: 197 - 209
Population pharmacokinetics of intravenous acetaminophen and its metabolites in major surgical patients Katie H. OwensPhilip G. M. MurphyDavid M. Reith Original Paper 21 May 2014 Pages: 211 - 221
Evaluation of bias, precision, robustness and runtime for estimation methods in NONMEM 7 Åsa M. JohanssonSebastian UeckertMats O. Karlsson Original Paper 07 May 2014 Pages: 223 - 238
Information contributed by meta-analysis in exposure–response modeling: application to phase 2 dose selection of guselkumab in patients with moderate-to-severe psoriasis Chuanpu HuYasmine WasfiHonghui Zhou Original Paper 23 May 2014 Pages: 239 - 250
Evaluation of sampling spacing in pharmacokinetic studies using six sigma method Tomasz GrabowskiAnna Raczyńska-PawelecJerzy Jan Jaroszewski Original Paper 22 June 2014 Pages: 251 - 260
Population pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator Andreas KrausePatrick BrossardJasper Dingemanse Original Paper 15 June 2014 Pages: 261 - 278
Methods to detect non-compliance and reduce its impact on population PK parameter estimates Leonid GibianskyEkaterina GibianskyFranziska Schaedeli Stark Original Paper 21 June 2014 Pages: 279 - 289