1. Editorial to the Themed Issue on Translational Modeling in Neuroscience

   • Peter L. Bonate

   Editorial 03 May 2013 Pages: 255 - 255

2. Quantitative systems pharmacology as an extension of PK/PD modeling in CNS research and development

   • Hugo Geerts
   • Athan Spiros
   • Robert Carr

   Original Paper 22 January 2013 Pages: 257 - 265

   

3. Modeling of PET data in CNS drug discovery and development

   • Katarina Varnäs
   • Andrea Varrone
   • Lars Farde

   Review Paper 10 May 2013 Pages: 267 - 279

   

4. Tracer-kinetic modeling of dynamic contrast-enhanced MRI and CT: a primer

   • Michael Ingrisch
   • Steven Sourbron

   Review Paper 06 April 2013 Pages: 281 - 300

   

5. In vitro, in vivo and in silico models of drug distribution into the brain

   • Scott G. Summerfield
   • Kelly C. Dong

   Review Paper 13 February 2013 Pages: 301 - 314

   

6. Utility of CSF in translational neuroscience

   • Elizabeth C. M. de Lange

   Original Paper Open access 12 February 2013 Pages: 315 - 326

   

7. The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid

   • Joost Westerhout
   • Jean Smeets
   • Elizabeth C. M. de Lange

   Original Paper Open access 29 March 2013 Pages: 327 - 342

   

8. Cerebral microdialysis in clinical studies of drugs: pharmacokinetic applications

   • Richard J. Shannon
   • Keri L. H. Carpenter
   • Peter J. Hutchinson

   Review Paper Open access 07 March 2013 Pages: 343 - 358

   

9. Development of a placebo effect model combined with a dropout model for bipolar disorder

   • Wan Sun
   • Thomas P. Laughren
   • Yaning Wang

   Original Paper 02 March 2013 Pages: 359 - 368

   

10. Disease progression and neuroscience

    • Nick Holford

    Review Paper 17 April 2013 Pages: 369 - 376

    

11. Modelling and simulation of placebo effect: application to drug development in schizophrenia

    • Venkatesh Pilla Reddy
    • Magdalena Kozielska
    • Johannes H. Proost

    Review Paper 12 January 2013 Pages: 377 - 388

    

12. Exposure–Response modeling of anti-depressant treatments: the confounding role of placebo effect

    • Navin Goyal
    • Roberto Gomeni

    Original Paper 21 December 2012 Pages: 389 - 399

    

13. Translational PK–PD modeling in pain

    • Ashraf Yassen
    • Paul Passier
    • Albert Dahan

    Review Paper 30 November 2012 Pages: 401 - 418