Population pharmacokinetic/pharmacodynamic modelling of the anti-TNF-α polyclonal fragment antibody AZD9773 in patients with severe sepsis James W. T. YatesShampa DasJohn Kemp Original Paper 23 September 2012 Pages: 591 - 599
Modeling of Functional Assessment Questionnaire (FAQ) as continuous bounded data from the ADNI database K. ItoM. M. HutmacherB. W. Corrigan Original Paper 19 September 2012 Pages: 601 - 618
Longitudinal FEV1 dose–response model for inhaled PF-00610355 and salmeterol in patients with chronic obstructive pulmonary disease Jace C. NielsenMatthew M. HutmacherJakob Ribbing Original Paper 23 September 2012 Pages: 619 - 634
A population pharmacokinetic model for the complex systemic absorption of ropivacaine after femoral nerve block in patients undergoing knee surgery François GaudreaultPierre DroletFrance Varin Original Paper 30 September 2012 Pages: 635 - 642
Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin Dhaval K. ShahNahor Haddish-BerhaneAlison Betts Original Paper 15 November 2012 Pages: 643 - 659
Optimised protocol design for the screening of analgesic compounds in neuropathic pain A. TanejaJ. NybergO. Della Pasqua Original Paper 30 November 2012 Pages: 661 - 671
Application of ED-optimality to screening experiments for analgesic compounds in an experimental model of neuropathic pain A. TanejaJ. NybergO. Della Pasqua Original Paper 30 November 2012 Pages: 673 - 681
Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer Lubna AbuqayyasJoseph P. Balthasar Original Paper 27 November 2012 Pages: 683 - 710
Applications of minimal physiologically-based pharmacokinetic models Yanguang CaoWilliam J. Jusko Original Paper 23 November 2012 Pages: 711 - 723
Letter to the editor regarding: “A reduction in between subject variability is not mandatory for selecting a new covariate” Mats O. KarlssonMartin Bergstrand Commentary 30 September 2012 Pages: 725 - 726
Reply to the editor of Journal of Pharmacokinetics and Pharmacodynamics Chakradhar V. LagishettyPavan VajjahStephen B. Duffull Commentary 02 October 2012 Pages: 727 - 727