1. The dynamics of Aβ distribution after γ-secretase inhibitor treatment, as determined by experimental and modelling approaches in a wild type rat

   • Leon M. Tai
   • Helmut Jacobsen
   • Hans-Peter Grimm

   Original Paper 06 April 2012 Pages: 227 - 237

   

2. Serial correlation in optimal design for nonlinear mixed effects models

   • Joakim Nyberg
   • Richard Höglund
   • Andrew C. Hooker

   Original Paper 14 March 2012 Pages: 239 - 249

   

3. Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model)

   • Jun Shen
   • Alison Boeckmann
   • Andrew Vick

   Original Paper 04 May 2012 Pages: 251 - 262

   

4. Analysis of exposure–response of CI-945 in patients with epilepsy: application of novel mixed hidden Markov modeling methodology

   • Maud Delattre
   • Radojka M. Savic
   • Marc Lavielle

   Original Paper 29 April 2012 Pages: 263 - 271

   

5. A pharmacokinetic model for the glycation of albumin

   • Oskar Alskär
   • Julia Korell
   • Stephen B. Duffull

   Original Paper 21 April 2012 Pages: 273 - 282

   

6. Misclassification and discordance of measured blood pressure from patient’s true blood pressure in current clinical practice: a clinical trial simulation case study

   • Yuyan Jin
   • Robert Bies
   • Rajanikanth Madabushi

   Original Paper 09 May 2012 Pages: 283 - 294

   

7. Optimal designs for composed models in pharmacokinetic–pharmacodynamic experiments

   • Holger Dette
   • Andrey Pepelyshev
   • Weng Kee Wong

   Original Paper 22 May 2012 Pages: 295 - 311