Volume 39, Issue 2 | Journal of Pharmacokinetics and Pharmacodynamics

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Volume 39, Issue 2

April 2012

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8 articles in this issue

Predicting the F(ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling
Ben-Fillippo Krippendorff
Diego A. Oyarzún
Wilhelm Huisinga
Original Paper Open access 08 March 2012 Pages: 125 - 139
Dose correction for the Michaelis–Menten approximation of the target-mediated drug disposition model
Xiaoyu Yan
Wojciech Krzyzanski
OriginalPaper 04 January 2012 Pages: 141 - 146
Population pharmacokinetic modelling of S-warfarin to evaluate the design of drug–drug interaction studies for CYP2C9
Kerenaftali Klein
Ivelina Gueorguieva
Leon Aarons
Original Paper 21 January 2012 Pages: 147 - 160
Population pharmacodynamic modeling of various extended-release formulations of methylphenidate in children with attention deficit hyperactivity disorder via meta-analysis
Holly Kimko
Ekaterina Gibiansky
Frank Wiegand
Original Paper 22 January 2012 Pages: 161 - 176
Evaluation of IPPSE, an alternative method for sequential population PKPD analysis
B. D. Lacroix
L. E. Friberg
M. O. Karlsson
Original Paper 21 January 2012 Pages: 177 - 193
First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development
Ashley Strougo
Thomas Eissing
Jan Freijer
Original Paper Open access 05 February 2012 Pages: 195 - 203
Moxifloxacin versus placebo modeling of the QT interval
Philippe Grosjean
Saïk Urien
Original Paper 17 February 2012 Pages: 205 - 215
Population pharmacokinetic and pharmacodynamic modeling of MNRP1685A in cynomolgus monkeys using two-target quasi-steady-state (QSS) model
Yan Xin
Hong Xiang
Shuang Bai
Original Paper 01 March 2012 Pages: 217 - 226