1. Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusions

   • Christine Ahlström
   • Lambertus A. Peletier
   • Johan Gabrielsson

   OriginalPaper Open access 04 November 2010 Pages: 1 - 24

   

2. Pharmacokinetic design optimization in children and estimation of maturation parameters: example of cytochrome P450 3A4

   • Marion Bouillon-Pichault
   • Vincent Jullien
   • Michel Tod

   OriginalPaper 04 November 2010 Pages: 25 - 40

   

3. The use of the SAEM algorithm in MONOLIX software for estimation of population pharmacokinetic-pharmacodynamic-viral dynamics parameters of maraviroc in asymptomatic HIV subjects

   • Phylinda L. S. Chan
   • Philippe Jacqmin
   • Barry Weatherley

   OriginalPaper Open access 19 November 2010 Pages: 41 - 61

   

4. Two bootstrapping routines for obtaining imprecision estimates for nonparametric parameter distributions in nonlinear mixed effects models

   • Paul G. Baverel
   • Radojka M. Savic
   • Mats O. Karlsson

   OriginalPaper 13 November 2010 Pages: 63 - 82

   

5. A new stochastic approach to multi-compartment pharmacokinetic models: probability of traveling route and distribution of residence time in linear and nonlinear systems

   • Liang Zhao
   • Na Li
   • Harry Yang

   OriginalPaper 17 December 2010 Pages: 83 - 104

   

6. Population pharmacodynamic model of the longitudinal FEV₁ response to an inhaled long-acting anti-muscarinic in COPD patients

   • Kai Wu
   • Michael Looby
   • Steve Pascoe

   OriginalPaper 20 November 2010 Pages: 105 - 119

   

7. Physiologically based pharmacokinetic model for topotecan in mice

   • Dhaval K. Shah
   • Joseph P. Balthasar

   OriginalPaper 20 November 2010 Pages: 121 - 142

   

8. Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats

   • Wei Gao
   • Sébastien Bihorel
   • William J. Jusko

   OriginalPaper 03 December 2010 Pages: 143 - 162

   

9. Erratum to: A new approach to the compartmental analysis in pharmacokinetics: fractional time evolution of diclofenac

   • Jovan K. Popović
   • Milica T. Atanacković
   • Teodor M. Atanacković

   Erratum 23 December 2010 Pages: 163 - 164