1. A latent variable approach for modeling categorical endpoints among patients with rheumatoid arthritis treated with golimumab plus methotrexate

   • Chuanpu Hu
   • Zhenhua Xu
   • Honghui Zhou

   OriginalPaper 16 July 2010 Pages: 309 - 321

   

2. Target-mediated drug disposition model for drugs that bind to more than one target

   • Leonid Gibiansky
   • Ekaterina Gibiansky

   OriginalPaper 29 July 2010 Pages: 323 - 346

   

3. A model of hypertension and proteinuria in cancer patients treated with the anti-angiogenic drug E7080

   • Ron J. Keizer
   • Anubha Gupta
   • Alwin D. R. Huitema

   OriginalPaper Open access 23 July 2010 Pages: 347 - 363

   

4. Lumping of physiologically-based pharmacokinetic models and a mechanistic derivation of classical compartmental models

   • Sabine Pilari
   • Wilhelm Huisinga

   OriginalPaper 27 July 2010 Pages: 365 - 405

   

5. An integrated pharmacokinetic–pharmacodynamic model for an Aurora kinase inhibitor

   • Hiroko Kamei
   • Robert C. Jackson
   • Fordyce A. Davidson

   OriginalPaper 08 August 2010 Pages: 407 - 434