Volume 36, Issue 6 | Journal of Pharmacokinetics and Pharmacodynamics

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Volume 36, Issue 6

December 2009

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6 articles in this issue

Assessing drug distribution in tissues expressing P-glycoprotein using physiologically based pharmacokinetic modeling: identification of important model parameters through global sensitivity analysis
Frederique Fenneteau
Jun Li
Fahima Nekka
OriginalPaper 22 October 2009 Pages: 495 - 522
D-optimal designs for parameter estimation for indirect pharmacodynamic response models
Leonid A. Khinkis
Wojciech Krzyzanski
William R. Greco
OriginalPaper 11 November 2009 Pages: 523 - 539
Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients
Brenda C. M. de Winter
Teun van Gelder
Ron A. A. Mathot
OriginalPaper Open access 11 November 2009 Pages: 541 - 564
Joint modeling of dizziness, drowsiness, and dropout associated with pregabalin and placebo treatment of generalized anxiety disorder
Bill Frame
Raymond Miller
Matthew M. Hutmacher
OriginalPaper 08 November 2009 Pages: 565 - 584
Prediction of pharmacokinetic profile of valsartan in human based on in vitro uptake transport data
Agnès Poirier
Anne-Christine Cascais
Thierry Lavé
OriginalPaper 20 November 2009 Pages: 585 - 611
A method for robust model order reduction in pharmacokinetics
Aristides Dokoumetzidis
Leon Aarons
OriginalPaper 20 November 2009 Pages: 613 - 628