Online first articles
Articles not assigned to an issue 29 articles
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A systematic evaluation of population pharmacokinetic models for polymyxin B in patients with liver and/or kidney dysfunction
Authors (first, second and last of 12)
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Five multivariate Duchenne muscular dystrophy progression models bridging six-minute walk distance and MRI relaxometry of leg muscles
Authors (first, second and last of 10)
This is part of 1 collection:
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Impact of covariate model building methods on their clinical relevance evaluation in population pharmacokinetic analyses: comparison of the full model, stepwise covariate model (SCM) and SCM+ approaches
Authors (first, second and last of 4)
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Model-based comparison of subcutaneous versus sublingual apomorphine administration in the treatment of motor fluctuations in Parkinson’s disease
Authors (first, second and last of 7)
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Docetaxel, cyclophosphamide, and epirubicin: application of PBPK modeling to gain new insights for drug-drug interactions
Authors (first, second and last of 6)
This is part of 1 collection:
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Longitudinal modeling of efficacy response in patients with lupus nephritis receiving belimumab
Authors (first, second and last of 4)
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On inductive biases for the robust and interpretable prediction of drug concentrations using deep compartment models
Authors (first, second and last of 5)
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Oral docetaxel plus encequidar – A pharmacokinetic model and evaluation against IV docetaxel
Authors (first, second and last of 10)
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Predicting efficacy assessment of combined treatment of radiotherapy and nivolumab for NSCLC patients through virtual clinical trials using QSP modeling
Authors (first, second and last of 7)
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Employing zero-inflated beta distribution in an exposure-response analysis of TYK2/JAK1 inhibitor brepocitinib in patients with plaque psoriasis
Authors (first, second and last of 7)
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A minimal physiologically based pharmacokinetic model to study the combined effect of antibody size, charge, and binding affinity to FcRn/antigen on antibody pharmacokinetics
Authors (first, second and last of 5)
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Subgroup identification-based model selection to improve the predictive performance of individualized dosing
Authors (first, second and last of 4)
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Population pharmacokinetics of the dual endothelin receptor antagonist aprocitentan in subjects with or without essential or resistant hypertension
Authors (first, second and last of 4)
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A population pharmacokinetics model of balovaptan to support dose selection in adult and pediatric populations
Authors (first, second and last of 8)
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Semi-mechanistic modeling of resistance development to β-lactam and β-lactamase-inhibitor combinations
Authors (first, second and last of 5)
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Expansion of platform physiologically-based pharmacokinetic model for monoclonal antibodies towards different preclinical species: cats, sheep, and dogs
Authors (first, second and last of 4)
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Prospective approaches to gene therapy computational modeling – spotlight on viral gene therapy
Authors (first, second and last of 4)
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Towards a platform quantitative systems pharmacology (QSP) model for preclinical to clinical translation of antibody drug conjugates (ADCs)
Authors (first, second and last of 8)
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Physiologically based pharmacokinetic model to predict drug–drug interactions with the antibody–drug conjugate enfortumab vedotin
Authors (first, second and last of 6)
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Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases
Authors (first, second and last of 4)
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Assessing the performance of QSP models: biology as the driver for validation
Authors (first, second and last of 4)
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Current practices for QSP model assessment: an IQ consortium survey
Authors (first, second and last of 17)
