1. Population pharmacokinetics of inotuzumab ozogamicin in relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma

   • May Garrett
   • Ana Ruiz-Garcia
   • Joseph Boni

   Original Paper Open access 11 March 2019 Pages: 211 - 222

   

2. Challenge model of TNF_α turnover at varying LPS and drug provocations

   • Felix Held
   • Edmund Hoppe
   • Johan Gabrielsson

   Original Paper Open access 18 February 2019 Pages: 223 - 240

   

3. Development of visual predictive checks accounting for multimodal parameter distributions in mixture models

   • Usman Arshad
   • Estelle Chasseloup
   • Mats O. Karlsson

   Original Paper Open access 09 April 2019 Pages: 241 - 250

   

4. Population pharmacokinetics and pharmacodynamics of piperacillin in critically ill patients during the early phase of sepsis

   • Waroonrat Sukarnjanaset
   • Sutep Jaruratanasirikul
   • Thitima Wattanavijitkul

   Original Paper 08 April 2019 Pages: 251 - 261

   

5. Pitfalls of using numerical predictive checks for population physiologically-based pharmacokinetic model evaluation

   • Anil R. Maharaj
   • Huali Wu
   • Michael Cohen-Wolkowiez

   Original Paper 23 April 2019 Pages: 263 - 272

   

6. Operating characteristics of stepwise covariate selection in pharmacometric modeling

   • Malidi Ahamadi
   • Anna Largajolli
   • Ferdous Gheyas

   Original Paper 24 April 2019 Pages: 273 - 285

   

7. Guiding dose selection of monoclonal antibodies using a new parameter (AFTIR) for characterizing ligand binding systems

   • Sameed Ahmed
   • Miandra Ellis
   • Andrew M. Stein

   Original Paper 29 April 2019 Pages: 287 - 304

   

8. Two-pore physiologically based pharmacokinetic model with de novo derived parameters for predicting plasma PK of different size protein therapeutics

   • Zhe Li
   • Dhaval K. Shah

   Original Paper 26 April 2019 Pages: 305 - 318