1. Dose-Dependence and Repeated-Dose Studies for Receptor/Gene-Mediated Pharmacodynamics of Methylprednisolone on Glucocorticoid Receptor Down-Regulation and Tyrosine Aminotransferase Induction in Rat Liver

   • Yu-Nien Sun
   • Debra C. DuBois
   • William J. Jusko

   OriginalPaper 17 July 2015 Pages: 619 - 648

2. Diffusion-Limited, but Not Perfusion-Limited, Compartmental Models Describe Cerebral Nitrous Oxide Kinetics at High and Low Cerebral Blood Flows

   • David J. Doolette
   • Richard N. Upton
   • Cliff Grant

   OriginalPaper 01 December 1998 Pages: 649 - 672

3. Pharmacokinetics and Relative Bioavailability of Carboxyamido-Triazole with Respect to Food and Time of Administration: Use of a Single Model for Simultaneous Determination of Changing Parameters

   • Kenneth S. Bauer
   • Elise C. Kohn
   • William D. Figg

   OriginalPaper 01 December 1998 Pages: 673 - 687

4. Robust Optimal Design for the Estimation of Hyperparameters in Population Pharmacokinetics

   • Michel Tod
   • France Mentré
   • Alain Mallet

   OriginalPaper 01 December 1998 Pages: 689 - 716

5. Implications for Clinical Pharmacodynamic Studies of the Statistical Characterization of an In Vitro Antiproliferation Assay

   • Laurence M. Levasseur
   • Hélène Faessel
   • William R. Greco

   OriginalPaper 01 December 1998 Pages: 717 - 733

6. Note: Caution in Use of Empirical Equations for Pharmacodynamic Indirect Response Models

   • Wojciech Krzyzanski
   • William J. Jusko

   OriginalPaper 01 December 1998 Pages: 735 - 741

7. Announcements

   Announcement 01 December 1998 Pages: 743 - 744