1. Prediction of the therapeutic dose for β-stimulants based on preclinical data: Application of oral dosage forms and aerosols to asthmatic patients

   • Kiyomi Ito
   • Naoko Yajima
   • Tatsuji Iga

   OriginalPaper 01 April 1993 Pages: 133 - 144

2. Stereoselective, competitive, and nonlinear plasma protein binding of ibuprofen enantiomers as determinedin vivo in healthy subjects

   • Jyoti K. Paliwal
   • David E. Smith
   • Grace H. Elta

   OriginalPaper 28 April 1993 Pages: 145 - 161

3. Nitroglycerin dinitrate metabolites do not affect the pharmacokinetics and pharmacodynamics of nitroglycerin in the dog: A preliminary report

   • Frank W. Lee
   • Jin Hu
   • Leslie Z. Benet

   OriginalPaper 03 May 1993 Pages: 163 - 173

4. Effect of phenobarbital andp-hydroxyphenobarbital glucuronide on acetaminophen metabolites in isolated rat hepatocytes: Use of a kinetic model to examine the rates of formation and egress

   • Scott D. Studenberg
   • Kim L. R. Brouwer

   OriginalPaper 01 April 1993 Pages: 175 - 194

5. Application of a simplified method to determine bioavailability of an oral dose of phenytoin

   • Anne L. Davis
   • Evan J. Begg
   • Garry G. Graham

   OriginalPaper 23 April 1993 Pages: 195 - 208

6. Effect of misspecification of the absorption process on subsequent parameter estimation in population analysis

   • Janet R. Wade
   • Andrew W. Kelman
   • Brian Whiting

   OriginalPaper 01 April 1993 Pages: 209 - 222

7. Targeting the systemic exposure of teniposide in the population and the individual using a stochastic therapeutic objective

   • David Z. D'Argenio
   • John H. Rodman

   OriginalPaper 28 April 1993 Pages: 223 - 251

8. Announcements

   Announcement 01 April 1993 Pages: 253 - 253