1. Multiconformational composite molecular potential fields in the analysis of drug action. I. Methodology and first evaluation using 5-HT and histamine action as examples

   • J. G. Vinter
   • K. I. Trollope

   Research Papers Pages: 297 - 307

2. Calculation of hydrophobic parameters directly from three-dimensional structures using comparative molecular field analysis

   • Ki Hwan Kim

   Research Papers Pages: 308 - 318

3. Modelling and mutation studies on the histamine H₁-receptor agonist binding site reveal different binding modes for H₁-agonists: Asp¹¹⁶ (TM3) has a constitutive role in receptor stimulation

   • Anton M. ter Laak
   • Hendrik Timmerman
   • Gabriëlle M. Donné-Op den Kelder

   Research Papers Pages: 319 - 330

4. Applications of momentum-space similarity

   • Peter T. Measures
   • Katherine A. Mort
   • David L. Cooper

   Research Papers Pages: 331 - 340

5. The atom assignment problem in automated de novo drug design. 1. Transferability of molecular fragment properties

   • M. T. Barakat
   • P. M. Dean

   Research Papers Pages: 341 - 350

6. The atom assignment problem in automated de novo drug design. 2. A method for molecular graph and fragment perception

   • M. T. Barakat
   • P. M. Dean

   Research Papers Pages: 351 - 358

7. The atom assignment problem in automated de novo drug design. 3. Algorithms for optimization of fragment placement onto 3D molecular graphs

   • M. T. Barakat
   • P. M. Dean

   Research Papers Pages: 359 - 372

8. Investigating the extension of pairwise distance pharmacophore measures to triplet-based descriptors

   • Andrew C. Good
   • Irwin D. Kuntz

   Research Papers Pages: 373 - 379

9. Calendar

   Events Pages: 380 - 380