1. Inhibitors of prolyl endopeptidase: Characterization of the pharmacophoric pattern using conformational analysis and 3D-QSAR

   • Thierry Langer
   • Camille G. Wermuth

   Research Papers Pages: 253 - 262

2. Use of the hydrogen bond potential function in a comparative molecular field analysis (CoMFA) on a set of benzodiazepines

   • Ki Hwan Kim
   • Giovanni Greco
   • Antonio Vittoria

   Research Papers Pages: 263 - 280

3. A preliminary 3D model for cytochrome P450 2D6 constructed by homology model building

   • Luc M. H. Koymans
   • Nico P. E. Vermeulen
   • Gabriëlle M. Donné-Op den Kelder

   Research Papers Pages: 281 - 289

4. Peptide mimetics as enzyme inhibitors: Use of free energy perturbation calculations to evaluate isosteric replacement for amide bonds in a potent HIV protease inhibitor

   • Piotr Cieplak
   • Peter A. Kollman

   Research Papers Pages: 291 - 304

5. An approximate but efficient method to calculate free energy trends by computer simulation: Application to dihydrofolate reductase-inhibitor complexes

   • Paul R. Gerber
   • Alan E. Mark
   • Wilfred F. van Gunsteren

   Research Papers Pages: 305 - 323

6. The use of an algorithmic method for small molecule superimpositions in the design of antiviral agents

   • Guy Diana
   • Edward P. Jaeger
   • Adi M. Treasurywala

   Research Papers Pages: 325 - 335

7. MEPSIM: A computational package for analysis and comparison of molecular electrostatic potentials

   • Ferran Sanz
   • Francesc Manaut
   • Elena López-de-Briñas

   Research Papers Pages: 337 - 347

8. Antifungal triazole alcohols: A comparative analysis of structure-activity, structure-teratogenicity and structure-therapeutic index relationships using the Multiple Computer-Automated Structure Evaluation (Multi-CASE) methodology

   • Gilles Klopman
   • Dmitri Ptchelintsev

   Research Papers Pages: 349 - 362

9. Calendar

   Events Pages: 363 - 363