1. Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors

   • Wolfgang Sippl
   • Jean-Marie Contreras
   • Camille G. Wermuth

   OriginalPaper Pages: 395 - 410

2. DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases

   • Todd J.A. Ewing
   • Shingo Makino
   • Irwin D. Kuntz

   OriginalPaper Pages: 411 - 428

3. Protein ligand docking based on empirical method for binding affinity estimation

   • Peng Tao
   • Luhua Lai

   OriginalPaper Pages: 429 - 446

4. Design of new selective inhibitors of cyclooxygenase-2 by dynamic assembly of molecular building blocks

   • Jiang Zhu
   • Haibo Yu
   • Yunyu Shi

   OriginalPaper Pages: 447 - 463

5. Selective inhibition of 6-phosphogluconate dehydrogenase from Trypanosoma brucei

   • Massimo Bertelli
   • Eman El-Bastawissy
   • Ian H. Gilbert

   OriginalPaper Pages: 465 - 475

6. Classification of protein disulphide-bridge topologies

   • J.M. Mas
   • P. Aloy
   • E. Querol

   OriginalPaper Pages: 477 - 487

7. Identification of cylin-dependent kinase 1 inhibitors of a new chemical type by structure-based design and database searching

   • Pascal Furet
   • Thomas Meyer
   • Heinz Fretz

   OriginalPaper Pages: 489 - 495