1. Editorial

   • Gerhard Klebe

   Legacy Pages: 113 - 113

2. Structure–affinity relationships for the binding of actinomycin D to DNA

   • José Gallego
   • Angel R. Ortiz
   • Federico Gago

   OriginalPaper Pages: 114 - 128

3. ANLIZE: A molecular mechanics force field visualization tool and its application to 18-crown-6

   • Lloyd D. Stolworthy
   • Randall B. Shirts

   OriginalPaper Pages: 129 - 134

4. Data modelling with neural networks: Advantages and limitations

   • D.J. Livingstone
   • D.T. Manallack
   • I.V. Tetko

   OriginalPaper Pages: 135 - 142

5. EVA: A new theoretically based molecular descriptor for use in QSAR/QSPR analysis

   • A.M. Ferguson
   • T. Heritage
   • P.J. Snaith

   OriginalPaper Pages: 143 - 152

6. Role of the tautomerism of 2-azaadenine and 2-azahypoxanthine in substrate recognition by xanthine oxidase

   • Begoña Hernández
   • Modesto Orozco
   • Francisco J. Luque

   OriginalPaper Pages: 153 - 162

7. Similarity searching in files of three-dimensional chemical structures: Representation and searching of molecular electrostatic potentials using field-graphs

   • David A. Thorner
   • Peter Willett
   • Robin Taylor

   OriginalPaper Pages: 163 - 174

8. Evaluation of a method for controlling molecular scaffold diversity in de novo ligand design

   • N.P. Todorov
   • P.M. Dean

   OriginalPaper Pages: 175 - 192

9. PRO_SELECT: Combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology

   • Christopher W. Murray
   • David E. Clark
   • Stephen C. Young

   OriginalPaper Pages: 193 - 207