Cancer and Metastasis Reviews
The transformation of biology from a descriptive, phenomenological discipline to one in which the regulatory principles are understood and predictably manipulated brings new opportunities to the study of cancer and the search for effective therapeutic modalities. Cancer and Metastasis Reviews offers a forum for critical review and discussion of these challenges.
Each issue presents five to seven different contributions on a single theme or topic, with an introductory essay from a distinguished individual in the field. Special emphasis is placed on subjects of relevance to the molecular and cellular biology of cancer metastasis and tumor progression, as well as to the treatment of metastatic disease. Occasional issues will be devoted to an in-depth clinical and biological analysis of a particular type of cancer.
The journal also reviews important recent developments in the biology and treatment of malignant disease, and highlights promising new directions.
Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting
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