1. Biography—Adi Gazdar

   Acknowledgments 18 February 2010 Pages: 1 - 1

   

2. Preface

   • Adi F. Gazdar

   EditorialNotes 28 January 2010 Pages: 3 - 4

3. Natural history of bronchial preinvasive lesions

   • Taichiro Ishizumi
   • Annette McWilliams
   • Stephen Lam

   OriginalPaper 30 January 2010 Pages: 5 - 14

   

4. Stepwise progression of pulmonary adenocarcinoma—clinical and molecular implications

   • Masayuki Noguchi

   OriginalPaper 29 January 2010 Pages: 15 - 21

   

5. EGFR mutations and the terminal respiratory unit

   • Yasushi Yatabe

   OriginalPaper 06 February 2010 Pages: 23 - 36

   

6. Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy

   • Adi F. Gazdar

   OriginalPaper 03 February 2010 Pages: 37 - 48

   

7. Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation

   • Kenichi Suda
   • Kenji Tomizawa
   • Tetsuya Mitsudomi

   OriginalPaper 28 January 2010 Pages: 49 - 60

   

8. Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

   • James P. Sullivan
   • John D. Minna
   • Jerry W. Shay

   OriginalPaper 23 January 2010 Pages: 61 - 72

   

9. Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer

   • Raj Chari
   • Kelsie L. Thu
   • Wan L. Lam

   OriginalPaper 29 January 2010 Pages: 73 - 93

   

10. Lung cancer: From single-gene methylation to methylome profiling

    • Gerwin Heller
    • Christoph C. Zielinski
    • Sabine Zöchbauer-Müller

    OriginalPaper 23 January 2010 Pages: 95 - 107

11. microRNAs and lung cancer: tumors and 22-mers

    • Liqin Du
    • Alexander Pertsemlidis

    OriginalPaper 04 February 2010 Pages: 109 - 122

12. Modeling prostate cancer: a perspective on transgenic mouse models

    • Varinder Jeet
    • Pamela J. Russell
    • Aparajita Khatri

    NON-THEMATIC REVIEW 10 February 2010 Pages: 123 - 142

    

13. The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment

    • Kelly K. Haagenson
    • Gen Sheng Wu

    NON-THEMATIC REVIEW 29 January 2010 Pages: 143 - 149

    

14. Targeted therapy for gastrointestinal stromal tumors: current status and future perspectives

    • Georgios S. Papaetis
    • Kostas N. Syrigos

    NON-THEMATIC REVIEW 30 January 2010 Pages: 151 - 170

    

15. Cetuximab in combination therapy: from bench to clinic

    • David E. Gerber
    • Hak Choy

    NON-THEMATIC REVIEW 08 February 2010 Pages: 171 - 180

    

16. DNA methylation markers in colorectal cancer

    • Myoung Sook Kim
    • Juna Lee
    • David Sidransky

    NON-THEMATIC REVIEW 06 February 2010 Pages: 181 - 206

    

17. p66Shc—a longevity redox protein in human prostate cancer progression and metastasis

    • Mythilypriya Rajendran
    • Paul Thomes
    • Ming-Fong Lin

    NON-THEMATIC REVIEW 29 January 2010 Pages: 207 - 222

    

18. Important role of integrins in the cancer biology

    • R. Rathinam
    • Suresh K. Alahari

    NON-THEMATIC REVIEW 30 January 2010 Pages: 223 - 237