1. Biographical sketch—Gregg L. Semenza

   • Gregg L. Semenza

   Acknowledgments 25 July 2007 Pages: 221 - 221

2. Hypoxia and cancer

   • Gregg L. Semenza

   PREFACE 03 April 2007 Pages: 223 - 224

3. Hypoxia in cancer: significance and impact on clinical outcome

   • Peter Vaupel
   • Arnulf Mayer

   OriginalPaper 18 April 2007 Pages: 225 - 239

4. Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment

   • Benjamin J. Moeller
   • Rachel A. Richardson
   • Mark W. Dewhirst

   OriginalPaper 14 April 2007 Pages: 241 - 248

5. Regulation of DNA repair in hypoxic cancer cells

   • Ranjit S. Bindra
   • Meredith E. Crosby
   • Peter M. Glazer

   OriginalPaper 06 April 2007 Pages: 249 - 260

6. Metastasis and stem cell pathways

   • Bryan C. Barnhart
   • M. Celeste Simon

   OriginalPaper 22 May 2007 Pages: 261 - 271

7. Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues

   • D. Lukashev
   • A. Ohta
   • M. Sitkovsky

   OriginalPaper 03 April 2007 Pages: 273 - 279

8. Hypoxia: A key regulator of angiogenesis in cancer

   • Debbie Liao
   • Randall S. Johnson

   OriginalPaper 29 June 2007 Pages: 281 - 290

9. Effects of hypoxia on tumor metabolism

   • Jung-whan Kim
   • Ping Gao
   • Chi V. Dang

   OriginalPaper 06 April 2007 Pages: 291 - 298

10. Regulation of tumor pH and the role of carbonic anhydrase 9

    • Pawel Swietach
    • Richard D. Vaughan-Jones
    • Adrian L. Harris

    OriginalPaper 06 April 2007 Pages: 299 - 310

11. Hypoxia and adaptive landscapes in the evolution of carcinogenesis

    • Robert J. Gillies
    • Robert A. Gatenby

    OriginalPaper 03 April 2007 Pages: 311 - 317

12. Hypoxia-driven selection of the metastatic phenotype

    • Richard Sullivan
    • Charles H. Graham

    OriginalPaper 26 April 2007 Pages: 319 - 331

13. Hypoxia, gene expression, and metastasis

    • Denise A. Chan
    • Amato J. Giaccia

    OriginalPaper 26 April 2007 Pages: 333 - 339

14. Targeting hypoxia cell signaling for cancer therapy

    • Giovanni Melillo

    OriginalPaper 06 April 2007 Pages: 341 - 352