1. Is paclitaxel/carboplatin really a useful regimen for ovarian cancer compared with platinum/doxorubicin/cyclophosphamide?

   • Toru Sugiyama

   EDITORIAL Pages: 163 - 163

2. Current topics and the clinical effects of target-based antineoplastic agents

   • Yoshihiko Maehara
   • Akinori Egashira
   • Yoshihiro Kakeji

   INTRODUCTION TO REVIEW ARTICLES Pages: 164 - 166

3. Methodological aspects of current problems in target-based anticancer drug development

   • Takeharu Yamanaka
   • Tatsuro Okamoto
   • Yoshihiko Maehara

   REVIEW ARTICLE Pages: 167 - 175

4. Treatment of chronic myeloid leukemia with imatinib mesylate

   • Ryuzo Ohno

   REVIEW ARTICLE Pages: 176 - 183

5. Gastrointestinal stromal tumor (GIST) and imatinib

   • Tetsuro Kubota

   REVIEW ARTICLE Pages: 184 - 189

6. Biological and clinical implications of EGFR mutations in lung cancer

   • Tetsuya Mitsudomi
   • Takayuki Kosaka
   • Yasushi Yatabe

   REVIEW ARTICLE Pages: 190 - 198

7. Trastuzumab and breast cancer: developments and current status

   • Eriko Tokunaga
   • Eiji Oki
   • Yoshihiko Maehara

   REVIEW ARTICLE Pages: 199 - 208

8. Molecular targeting therapy for renal cell carcinoma

   • Masatoshi Eto
   • Seiji Naito

   REVIEW ARTICLE Pages: 209 - 213

9. Management of sentinel lymph nodes in malignant skin tumors using dynamic lymphoscintigraphy and the single-photon-emission computed tomography/computed tomography combined system

   • Tsuyoshi Ishihara
   • Atsushi Kaguchi
   • Tomomichi Ono

   ORIGINAL ARTICLE Pages: 214 - 220

10. Historical control study of paclitaxel–carboplatin (TJ) versus conventional platinum-based chemotherapy (CAP) for epithelial ovarian cancer

    • Reiko Numazaki
    • Etsuko Miyagi
    • Fumiki Hirahara

    ORIGINAL ARTICLE Pages: 221 - 228

11. Malignant change secondary to fibrous dysplasia

    • Manabu Hoshi
    • Seiichi Matsumoto
    • Noriyoshi Kawaguchi

    ORIGINAL ARTICLE Pages: 229 - 235

12. Primary chemotherapy-associated effect of second-line chemotherapy on survival of patients with advanced ovarian cancer

    • Seiji Isonishi
    • Masanori Hirama
    • Tadao Tanaka

    ORIGINAL ARTICLE Pages: 236 - 242

13. Carcinomatous meningitis from non-small-cell lung cancer responding to gefitinib

    • Mitsuaki Sakai
    • Shigemi Ishikawa
    • Yuzuru Sakakibara

    CASE REPORT Pages: 243 - 245

14. Cholangiocellular carcinoma that produced both granulocyte-colony-stimulating factor and parathyroid hormone-related protein

    • Tetsuro Sohda
    • Hiroshi Shiga
    • Shotaro Sakisaka

    CASE REPORT Pages: 246 - 249

15. Positron emission tomography with 18F-fluoro-2-deoxyglucose for the detection of recurrent ovarian cancer

    • Yukihiro Hama

    LETTER TO THE EDITOR Pages: 250 - 251