Background
Toxoplasmosis is a zoonosis caused by a coccidian protozoan, Toxoplasma gondii.
Methods
The study included 407 non-pregnant women with high risk for toxoplasmosis, presented to the Infectious Diseases Clinic in Oradea in the period 01.01.2009-31.12.2012. By MEIA (Microparticle Enzyme Immunoassay) performed in Bioclinica laboratories, values of Toxoplasma IgM and IgG antibodies were determined and by EIA (Enzyme Immunoassay), the values of IgA Toxoplasma antibodies, as well as the dynamic tracing of their evolution over a period of 12 month.
Results
The results of investigations showed that 24.3% of non-pregnant women had acute toxoplasmosis, 25.6% had acute toxoplasmosis in their past, at a rate of 60% the serology was completely negative. Most cases of acute toxoplasmosis were diagnosed in spring and autumn (p=0.0373). The most affected range was the age group 21-25 and 26-30 (p<0.0001). The gynecologist and the patients’ own initiative has an important role in guiding them to make analysis (p<0.0001). The main reason for presentation to the Infectious Clinic was the appearance of adenopathies with cervical localization (p=0.0001). The optimum period of time necessary to achieve negative level of IgM and IgA Toxoplasma was between 3 to 6 months after presentation (p<0.0001).
Conclusion
The infection with Toxoplasma gondii affects especially young women; most of the cases appear in spring and autumn.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
This article is published under an open access license. Please check the 'Copyright Information' section either on this page or in the PDF for details of this license and what re-use is permitted. If your intended use exceeds what is permitted by the license or if you are unable to locate the licence and re-use information, please contact the Rights and Permissions team.
About this article
Cite this article
Csep, A. Clinical and biological correlations in acute toxoplasmosis. BMC Infect Dis 14 (Suppl 7), P15 (2014). https://doi.org/10.1186/1471-2334-14-S7-P15
Published:
DOI: https://doi.org/10.1186/1471-2334-14-S7-P15