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Hybrid nickel-molybdenum bimetallic sulfide nanozymes for antibacterial and antibiofouling applications

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Abstract

Biofouling is ubiquitous in nature and is one of the biggest threats to medical, food, and engineering applications. Creating artificial nanomaterials (nanozymes) to copy the functionalities of natural enzymes is showing as an emerging technology for thwarting biofilm. Molybdenum disulfide (MoS2) is a potential nanozyme for biofilm control, but the practical feasibility is jeopardized by the insufficient catalytic efficiency. Herein, a hybrid nickel-molybdenum bimetallic sulfide (L-NiMoS2) is deliberately fabricated to ensure the abundant active site exposure. The optimized L-NiMoS2 exhibits a superior haloperoxidase-like activity for catalyzing the oxidation of Br− into biocidal HOBr/OBr− in the presence of H2O2, with a catalytic kinetic rate value being 2.6 and 135.7 times higher than the pristine NiMoS2 and MoS2, respectively. By performing haloperoxidase-like activity, L-NiMoS2 nanozyme shows extraordinary antibacterial capacity and antibiofouling performance in the open ocean. Collectively, this work provides an attractive strategy to create highly efficient MoS2 nanozyme through textural engineering and is expected to ignite further explorations of nanozymes for antibacterial and antibiofouling applications.

Graphical Abstract

A hybrid defective nickel-molybdenum bimetallic sulfide is constructed to mimic naturally occurring haloperoxidase, yielding superior antibiofouling ability in bio-aggressive seawater.

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Funding

This work has been financially supported by the Hainan Science and Technology Major Project (ZDKJ2020011), the National Natural Science Foundation of China (52172195), the Start-up Research Foundation of Hainan University (KYQD(ZR)1907), and the Innovation Platform for Academicians of Hainan Province (HD-YSZX-202007 and HD-YSZX-202008).

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Authors and Affiliations

  1. Institute of New Energy Materials, School of Materials Science and Engineering, Tianjin University, Tianjin, 300072, People’s Republic of China

    Wei Wang & Xiwen Du

  2. State Key Laboratory of Marine Resource Utilization in South China Sea, Hainan University, Haikou, 570228, People’s Republic of China

    Wei Wang, Qiang Luo, Linqian Li, Shipeng Chen, Yifan Wang & Ning Wang

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  1. Wei Wang
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  2. Qiang Luo
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  3. Linqian Li
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  5. Yifan Wang
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  6. Xiwen Du
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  7. Ning Wang
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Contributions

Ning Wang and Qiang Luo supervised and conceptualized the project. Qiang Luo and Wei Wang designed and conducted the experiments. Linqian Li, Shipeng Chen, Yifan Wang, and Xiwen Du contributed to the discussions and provided critical revisions.

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Correspondence to Qiang Luo or Ning Wang.

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Wang, W., Luo, Q., Li, L. et al. Hybrid nickel-molybdenum bimetallic sulfide nanozymes for antibacterial and antibiofouling applications. Adv Compos Hybrid Mater 6, 139 (2023). https://doi.org/10.1007/s42114-023-00718-0

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