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Synthesis of 2-Aryl-2,3-Dihydroquinazolin-4(1H)-One Derivatives Using Lactic Acid as a Green, Natural and Inexpensive Catalyst in Water

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Abstract

In this work, we used lactic acid as a green and inexpensive catalyst for the synthesis of 2,3-dihydro-2-phenylquinazolin-4(1H)-ones via the cyclocondensation of 2-aminobenzamide and aromatic aldehydes in water. The main advantages of this reaction are green conditions, short reaction times, relatively high yields and simple separation of products.

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Acknowledgements

We gratefully appreciate the financial support from the Research Council of University of Sistan and Baluchestan.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, PO Box 98135-674, Zahedan, Iran

    Tayebeh Jazinizadeh, Malek Taher Maghsoodlou & Reza Heydari

Authors
  1. Tayebeh Jazinizadeh
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  2. Malek Taher Maghsoodlou
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  3. Reza Heydari
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Correspondence to Malek Taher Maghsoodlou.

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Jazinizadeh, T., Maghsoodlou, M.T. & Heydari, R. Synthesis of 2-Aryl-2,3-Dihydroquinazolin-4(1H)-One Derivatives Using Lactic Acid as a Green, Natural and Inexpensive Catalyst in Water. Iran J Sci Technol Trans Sci 42, 1929–1933 (2018). https://doi.org/10.1007/s40995-017-0362-2

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  • DOI: https://doi.org/10.1007/s40995-017-0362-2

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