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The interesting picture: simultaneous occurrence of myeloma cast nephropathy, light chain deposition disease and light chain proximal tubulopathy in a patient with multiple myeloma

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Fig. 1

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All data generated in this study are included in the main manuscript.

References

  1. Dimopoulos MA, Sonneveld P, Leung N, Merlini G, Ludwig H, Kastritis E, Goldschmidt H, Joshua D, Orlowski RZ, Powles R, Vesole DH, Garderet L, Einsele H, Palumbo A, Cavo M, Richardson PG, Moreau P, San Miguel J, Rajkumar SV, Durie BG, Terpos E (2016) International myeloma working group recommendations for the diagnosis and management of myeloma-related renal impairment. J Clin Oncol: Off J Am Soc Clin Oncol 34(13):1544–1557. https://doi.org/10.1200/jco.2015.65.0044

    Article  Google Scholar 

  2. Hogan JJ, Alexander MP, Leung N (2019) Dysproteinemia and the kidney: core curriculum 2019. Am J Kidney Dis 74(6):822–836. https://doi.org/10.1053/j.ajkd.2019.04.029

    Article  PubMed  Google Scholar 

  3. Buxbaum J, Gallo G (1999) Nonamyloidotic monoclonal immunoglobulin deposition disease. Light-chain, heavy-chain, and light- and heavy-chain deposition diseases. Hematol Oncol Clin North Am 13(6):1235–1248. https://doi.org/10.1016/s0889-8588(05)70123-4

    Article  CAS  PubMed  Google Scholar 

  4. Lorenz EC, Sethi S, Poshusta TL, Ramirez-Alvarado M, Kumar S, Lager DJ, Fervenza FC, Leung N (2010) Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease. Nephrol Dial Transplant 25(4):1340–1343. https://doi.org/10.1093/ndt/gfp735

    Article  PubMed  Google Scholar 

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Funding

This work was supported by the National Natural Science Foundation of China (Grant No. 81470956). The funders had no role in study design, data collection and analysis, interpretation of the data, decision to publish, or preparation of the manuscript.

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Authors and Affiliations

Authors

Contributions

Z.S.L drafted this manuscript and collected clinical data; X.J.Y interpreted the histopathological data; S.X.W, F.D.Z and M.H.Z designed this case study and revised the manuscript. All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Fu-De Zhou.

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Conflict of interest

The authors declare that they have no conflicts of interests.

Ethics approval

This study was performed in accordance with the Helsinki Declaration, and approved by the ethics committee of the Peking University first hospital. Written informed consent were obtained from the patient.

Informed consent

Informed written consent was obtained from the patient for publication of this case report and accompanying images. A Copy of the written consent is available for review by the Editor of this journal.

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Lin, ZS., Yu, XJ., Wang, SX. et al. The interesting picture: simultaneous occurrence of myeloma cast nephropathy, light chain deposition disease and light chain proximal tubulopathy in a patient with multiple myeloma. J Nephrol 33, 649–651 (2020). https://doi.org/10.1007/s40620-020-00764-7

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  • DOI: https://doi.org/10.1007/s40620-020-00764-7

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