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Evaluating the effects of mobile health intervention on weight management, glycemic control and pregnancy outcomes in patients with gestational diabetes mellitus

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Abstract

Purpose

To explore the effects of mobile health (mHealth) intervention on pregnancy weight management, blood glucose control and pregnancy outcomes.

Methods

A total of 124 patients with gestational diabetes mellitus (GDM) were selected. Patients were randomly divided into two groups. The 60 patients in the control group received standard outpatient treatment, while the remaining 64 patients received a nurse’s online guidance both through a mobile medical App installed on their phone and through regular offline clinical treatment in the mHealth group. Patients were treated for an average of 13 weeks and general conditions, compliance, blood glucose, glycosylated hemoglobin, weight gain, pregnancy, and neonatal outcomes were monitored in both groups longitudinally.

Results

The mHealth group demonstrated higher levels of compliance (83.3 ± 12.5% vs. 70.4 ± 10.1%, t = − 6.293, df = 122, p < 0.001), lower frequency of outpatient service (8.1 ± 1.3 vs. 11.2 ± 1.1, t = 14.285, df = 122, p < 0.001), lower hemoglobin A1C before delivery (4.7 ± 0.2 vs. 5.3 ± 0.3, t = 13.216, df = 122, p < 0.001) as well as the rates of off-target measurements both fasting (4.6 ± 0.4% vs. 8.3 ± 0.6%, t = 40.659, df = 122, p < 0.001) and 2 h post-prandial (7.9 ± 0.7% vs. 14.7 ± 0.8%, t = 50.746, df = 122, p < 0.001). Weight gain in the mHealth group was less than control group (3.2 ± 0.8 vs. 4.8 ± 0.7, t = 11.851, df = 122 p < 0.001).

Conclusion

Mobile health intervention management of gestational diabetes mellitus improves patients’ compliance and blood glucose control, and reduces weight gain, thereby reducing the rates of complications in both pregnant women and fetuses during delivery during pregnancy.

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Funding

This work was supported by the National Natural Science Foundation of China (no. 81470187). Natural Science Foundation of Tianjin (no. 15ZXHLSY00460). Startup Funding of Scientific Research, Tianjin Medical University Metabolic Diseases Hospital and Tianjin Institute of Endocrinology (no. 2016DX02).

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Authors and Affiliations

  1. NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital, Tianjin Institute of Endocrinology, Tianjin, 300070, China

    H. Guo, Y. Zhang, P. Li, P. Zhou, L.-M. Chen & S.-Y. Li

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  1. H. Guo
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  2. Y. Zhang
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  3. P. Li
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  4. P. Zhou
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  5. L.-M. Chen
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  6. S.-Y. Li
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Correspondence to S.-Y. Li.

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Conflict of interest

The authors declare that they have no competing interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.”

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Informed consent was obtained from all individual participants included in the study.

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Guo, H., Zhang, Y., Li, P. et al. Evaluating the effects of mobile health intervention on weight management, glycemic control and pregnancy outcomes in patients with gestational diabetes mellitus. J Endocrinol Invest 42, 709–714 (2019). https://doi.org/10.1007/s40618-018-0975-0

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  • DOI: https://doi.org/10.1007/s40618-018-0975-0

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