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Associations between binge eating, depressive symptoms and anxiety and weight regain after Roux-en-Y gastric bypass surgery

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Abstract

Background

Weight regain (WR) after bariatric surgery (BS) is frequent.

Objective

The aim of this study was to evaluate whether the occurrence of psychiatric disorders would be associated with short- and long-term WR after BS.

Methods

Ninety-six patients (77.6% female, age 40.2 ± 10.1 years, BMI of 50 ± 8.2 kg/m2) from the Obesity and Bariatric Surgery Outpatient Clinic of the Universidade Federal São Paulo completed the Questionnaire on Eating and Weight Patterns-Revised, the Beck Depression Inventory and an anxiety inventory to assess the occurrence of binge eating, depressive symptoms (DS) and anxious symptoms (AS) before and after short-term and long-term BS.

Results

Twenty-four months after BS, the prevalence of binge eating, depression and anxiety decreased from 100 to 13%, 100 to 15% and 43 to 4%, respectively. The mean WR of 35.2 ± 17.3% of weight loss occurred in nine patients after 24 months and was associated with binge eating (p = 0.002) but not with DS or AS. At long-term follow-up (12 ± 1.5 years), 67% had a mean WR of 50.3 ± 24.9%. The prevalence of binge eating, DS and AS were 48%, 46% and 63%, respectively, in this group, and significant associations were observed between WR and binge eating (p = 0.001), DS (p = 0.029) and AS (p = 0.001). Furthermore, the number of psychiatric disorders was inversely associated with the percentage of weight loss (p < 0.05) and positively associated with WR (p < 0.05).

Conclusion

Weight regain was associated with the occurrence of binge eating in the short and long term after BS, whereas the occurrence of depressive and anxious symptoms was associated with WR only in the long term.

Level III

Evidence obtained from well-designed cohort or case–control analytic studies.

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Funding

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Authors and Affiliations

  1. Department of Medicine, Division Endocrinology and Metabolism, Universidade Federal de São Paulo, End: Street Leandro Duprat, 365, São Paulo, 04025-010, Brazil

    Cristina Cardoso Freire, Maria Teresa Zanella, Maria Isabel Rodrigues Matos & Glaucia Carneiro

  2. Department of Medicine, Obesity and Metabolism Syndrome Outpatient Service, Universidade de São Paulo, São Paulo, Brazil

    Adriano Segal

  3. Department of Surgery, Division of Surgical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil

    Carlos Haruo Arasaki

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  1. Cristina Cardoso Freire
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  2. Maria Teresa Zanella
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  3. Adriano Segal
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  5. Maria Isabel Rodrigues Matos
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  6. Glaucia Carneiro
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Correspondence to Cristina Cardoso Freire.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the ethics committee of Universidade Federal de São Paulo and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Freire, C.C., Zanella, M.T., Segal, A. et al. Associations between binge eating, depressive symptoms and anxiety and weight regain after Roux-en-Y gastric bypass surgery. Eat Weight Disord 26, 191–199 (2021). https://doi.org/10.1007/s40519-019-00839-w

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  • DOI: https://doi.org/10.1007/s40519-019-00839-w

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