Skip to main content
SpringerLink
Log in

A rare case of bilateral testicular metastasis from ileocecal NET: multiparametric US detection

  • Pictorial Essay
  • Published:
Journal of Ultrasound Aims and scope Submit manuscript

Abstract

Testicular metastasis are rare findings and bilateral metastasis of testes are extremely rare. Here we are describing for the first time a case of bilateral testicular metastasis in a patient with a known ileocecal valve NET using an in-depth ultra-sound studying including microvascular flow imaging (MV-flow), ultra-sound new technique, able to detect small vessel slow-signal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Modlin IM, Lye KD, Kidd M (2003) A 5-decade analysis of 13,715 carcinoid tumors. Cancer 97(4):934–959. https://doi.org/10.1002/cncr.11105 (PMID: 12569593)

    Article  PubMed  Google Scholar 

  2. Riihimäki M, Hemminki A, Sundquist K, Sundquist J, Hemminki K (2016) The epidemiology of metastases in neuroendocrine tumors. Int J Cancer 139(12):2679–2686. https://doi.org/10.1002/ijc.30400 (Epub 2016 Sep 9, PMID: 27553864)

    Article  CAS  PubMed  Google Scholar 

  3. De Zordo T, Stronegger D, Pallwein-Prettner L, Harvey CJ, Pinggera G, Jaschke W, Aigner F, Frauscher F (2013) Multiparametric ultrasonography of the testicles. Nat Rev Urol 10(3):135–148. https://doi.org/10.1038/nrurol.2012.255 (Epub 2013 Jan 22, PMID: 23338520)

    Article  PubMed  Google Scholar 

  4. Kudo M, Tochio H (2008) Intranodular blood supply correlates well with biological malignancy grade determined by tumor growth rate in pathologically proven hepatocellular carcinoma. Oncology 75(Suppl 1):55–64. https://doi.org/10.1159/000173425 (Epub 2008 Dec 17, PMID: 19092273)

    Article  CAS  PubMed  Google Scholar 

  5. Dieckmann KP, Düe W, Loy V (1988) Intrascrotal metastasis of renal cell carcinoma. Case reports and review of the literature. Eur Urol 15(3–4):297–301. https://doi.org/10.1159/000473457 (PMID: 3063545)

    Article  CAS  PubMed  Google Scholar 

  6. Manikandan R, Nathaniel C, Reeve N, Brough RJ (2006) Bilateral testicular metastases from prostatic carcinoma. Int J Urol 13(4):476–477. https://doi.org/10.1111/j.1442-2042.2006.01329.x (PMID: 16734881)

    Article  PubMed  Google Scholar 

  7. Tufano A, Flammia RS, Antonelli L, Minelli R, Franco G, Leonardo C, Cantisani V (2021) The value of contrast-enhanced ultrasound (CEUS) in differentiating testicular masses: a systematic review and meta-analysis. Appl Sci 11:8990. https://doi.org/10.3390/app11198990

    Article  CAS  Google Scholar 

  8. Huang DY, Sidhu PS (2012) Focal testicular lesions: colour Doppler ultrasound, contrast-enhanced ultrasound and tissue elastography as adjuvants to the diagnosis. Br J Radiol 85 Spec No 1(Spec Iss 1):S41-53. https://doi.org/10.1259/bjr/30029741 (Epub 2012 Jun 6, PMID: 22674702; PMCID: PMC3746409)

    Article  CAS  PubMed  Google Scholar 

  9. Huang H, Ling W, Qiu T, Luo Y (2018) Ultrasonographic features of testicular metastasis from renal clear cell carcinoma that mimics a seminoma: a case report. Medicine (Baltimore) 97(40):e12728. https://doi.org/10.1097/MD.0000000000012728 (PMID:30290683; PMCID:PMC6200504)

    Article  PubMed  Google Scholar 

  10. Kang HJ, Lee JM, Jeon SK, Ryu H, Yoo J, Lee JK, Han JK (2019) Microvascular flow imaging of residual or recurrent hepatocellular carcinoma after transarterial chemoembolization: comparison with color/power Doppler imaging. Korean J Radiol 20(7):1114–1123. https://doi.org/10.3348/kjr.2018.0932 (PMID:31270975; PMCID:PMC6609430)

    Article  PubMed  PubMed Central  Google Scholar 

  11. Chen X, Wei X, Zhao S, Huang H, Wang W, Qiu J, Chen X, Cheng C, Tian Z, Rychik J (2020) Characterization of placental microvascular architecture by MV-flow imaging in normal and fetal growth-restricted pregnancies. J Ultrasound Med. https://doi.org/10.1002/jum.15531 (Epub ahead of print, PMID: 33073868)

    Article  PubMed  PubMed Central  Google Scholar 

  12. Dall’Asta A, Grisolia G, Volpe N, Schera G, Sorrentino F, Frusca T, Ghi T (2020) Prenatal visualisation of the torcular herophili by means of a Doppler technology highly sensitive for low-velocity flow in the expert assessment of the posterior fossa: a prospective study. BJOG. https://doi.org/10.1111/1471-0528.16392 (Epub ahead of print, PMID: 32619035)

    Article  PubMed  Google Scholar 

  13. Rocher L, Gennisson JL, Ferlicot S, Criton A, Albiges L, Izard V, Bellin MF, Correas JM (2018) Testicular ultrasensitive Doppler preliminary experience: a feasibility study. Acta Radiol 59(3):346–354. https://doi.org/10.1177/0284185117713350 (Epub 2017 Jun 1, PMID: 28569117)

    Article  PubMed  Google Scholar 

  14. Lee YS, Kim MJ, Han SW, Lee HS, Im YJ, Shin HJ, Lee MJ (2016) Superb microvascular imaging for the detection of parenchymal perfusion in normal and undescended testes in young children. Eur J Radiol 85(3):649–656. https://doi.org/10.1016/j.ejrad.2015.12.023 (Epub 2015 Dec 30, PMID: 26860680)

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Advanced Biomedical Sciences, University of Naples Federico II, via S. Pansini 5, 80131, Naples, Italy

    Marika Santarsiere, Mariateresa Rumolo, Biagio F. Menna, Emilia Vergara, Arturo Brunetti & Pietro Gisonni

  2. Department Life and Health “V. Tiberio”, University of Molise, Francesco De Sanctis st 1, 86100, Campobasso, Italy

    Rocco Minelli

  3. Unit of Radiology and Ultrasound, A.O.R.N. Santobono-Pausilipon, Pausilipon Hospital, Naples, Italy

    Carmela Brillantino & Eugenio Rossi

Authors
  1. Marika Santarsiere
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mariateresa Rumolo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Biagio F. Menna
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Emilia Vergara
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Rocco Minelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Carmela Brillantino
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Eugenio Rossi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Arturo Brunetti
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Pietro Gisonni
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rocco Minelli.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical statements and Informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki declaration of 1975, and its late amandments. Additional informed consented was obtained from all patients for which indentifyng information is not included in this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Santarsiere, M., Rumolo, M., Menna, B.F. et al. A rare case of bilateral testicular metastasis from ileocecal NET: multiparametric US detection. J Ultrasound 26, 223–227 (2023). https://doi.org/10.1007/s40477-022-00657-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40477-022-00657-4

Keywords

Search

Navigation