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Direct pulp capping (DPC) in primary molars using (3Mix-MP) and the characteristics of the carious lesion as predictor factors for its success: a randomized controlled trial

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European Archives of Paediatric Dentistry Aims and scope Submit manuscript

Abstract

Purpose

This study aimed at the following: (a) To evaluate the effectiveness of direct pulp capping (DPC) in children’s primary molars using a combination of three antibiotics (3Mix-MP) as direct pulp capping materials compared with Calcium Hydroxide and (b) to assess the impact of pulp exposure diameter, its location and restoration extent on the success rate of the technique.

Methods

This was a randomized double-blind, parallel, two-arm controlled trial. Forty-four primary molars with deep active caries, whose removal resulted in pulp exposures, were treated with direct pulp capping and were allocated randomly into two groups: Group A, DPC with 3Mix-MP; and group B, DPC with Calcium Hydroxide (CH). All teeth were restored with composite resin restorations. The exposures were classified according to their diameter, location and number of the filling surfaces. Clinical follow-ups were performed at intervals of 3 months for 1 year, and radiographical follow-ups were done after 6–12 months. Data were assessed using Chi-squared test (χ2) at a 0.05 level of significance and binary logistic regression was performed to determine the effect of the characteristics of the carious lesion on success rates.

Results

The success rate of the technique was 54.5% in group A and 77.3% in group B, but the difference was not statistically significant. The pulp exposure diameter, its location and the number of the filling surfaces did not affect the success rate significantly.

Conclusion

(a) Direct pulp capping in primary teeth achieved comparable success rates with no significant difference between 3Mix-MP and Calcium hydroxide. (b) The exposure location, its diameter and the extent of the restoration had no significant impact on the success rates of direct pulp capping in primary teeth.

Trial registration

ISRCTN, ISRCTN13525994. Registered 31 October 2018 – Retrospectively registered, (http:// www.isrctn.com/ISRCTN13525994).

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Data availability

The datasets used and/or analysed during the current study available from the corresponding author on reasonable request.

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Acknowledgement

The staff at the Department of Pediatric Dentistry is acknowledged for their assistance.

Funding

The study was funded by Tishreen University, Latakia. Syria (ref: 4075/20-3). The funding body had no role in data handling nor in the writing of this manuscript.

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Authors and Affiliations

  1. Department of Pediatric Dentistry, Faculty of Dentistry, Tishreen University, Lattakia, Syria

    H. Ali & N. Raslan

Authors
  1. H. Ali
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  2. N. Raslan
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Contributions

We declare that all authors have made substantial contributions. NR designed the research study. HA performed the research including patient recruitment and data collection. NR and HA analysed the data. HA prepared the manuscript draft with important intellectual input from NR. NR revised the manuscript. All authors approved the final manuscript. All authors had complete access to the study data. All authors agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Corresponding author

Correspondence to H. Ali.

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Conflict of interest

The authors declare that they have no competing interests.

Ethical approval

The IRB of Tishreen University had approved the study. Approval No. 3179 was obtained in session (No.18), held on August 2, 2016.

Informed consent to participate

A written consent was secured from the parents prior to submit an image of their child's teeth.

Informed consent for publication

A written consent was secured from the parents prior to submit an image of their child's teeth.

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Ali, H., Raslan, N. Direct pulp capping (DPC) in primary molars using (3Mix-MP) and the characteristics of the carious lesion as predictor factors for its success: a randomized controlled trial. Eur Arch Paediatr Dent 22, 633–642 (2021). https://doi.org/10.1007/s40368-020-00600-3

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  • DOI: https://doi.org/10.1007/s40368-020-00600-3

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