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A Review of Management Strategies for Nociceptive and Neuropathic Ocular Surface Pain

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Abstract

Despite being a common presenting symptom to eye-care clinics, many ophthalmologists have difficulty diagnosing and managing ocular surface pain. The purpose of this review is to discuss potential causes of ocular surface pain, focusing on both nociceptive and neuropathic aetiologies. Specifically, we outline an approach to the diagnosis of ocular surface pain and focus on various management strategies, providing supporting evidence on the efficacy of various treatments.

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Authors and Affiliations

  1. University of Miami Miller School of Medicine, 1600 NW 10th Ave, Miami, FL, 33136, USA

    Harrison Dermer & Despoina Theotoka

  2. California Northstate University College of Medicine, 9700 W Taron Drive, Elk Grove, CA, 95757, USA

    Daniella Lent-Schochet

  3. Universidad El Bosque, NO 131 A AK. 9 #131a2, Bogota D.C., Colombia

    Christian Paba

  4. Imperial College London, School of Medicine, Kensington, London, SW7 2DD, UK

    Abdullah A. Cheema

  5. McGovern Medical School, University of Texas Health Science Center At Houston, Houston, TX, USA

    Ryan S. Kim

  6. Bascom Palmer Eye Institute, 900 NW 17th Street, Miami, FL, 33136, USA

    Anat Galor

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  1. Harrison Dermer
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Correspondence to Anat Galor.

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Funding

Supported by the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences Research EPID-006-15S (Dr Galor), R01EY026174 (Dr Galor), NIH Center Core Grant P30EY014801 and Research to Prevent Blindness Unrestricted Grant.

Conflict of Interest

Authors Dermer, Lent-Schochet, Theotoka, Paba, Cheema, and Kim have no conflicts of interest to disclose. Dr. Anat Galor has no conflicts of interest to declare and her grant and consulting activities have not influenced the content of this manuscript.

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Dermer, H., Lent-Schochet, D., Theotoka, D. et al. A Review of Management Strategies for Nociceptive and Neuropathic Ocular Surface Pain. Drugs 80, 547–571 (2020). https://doi.org/10.1007/s40265-020-01282-3

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