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Diastereoselective synthesis of 1,10-dihydropyrrolo[1,2-a][1,10]phenanthroline derivatives via 1,3-dipolar cycloaddition reaction

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Abstract

The functionalized 1,10-dihydropyrrolo[1,2-a][1,10]phenanthroline derivatives were synthesized in good yields and with high diastereoselectivity by 1,3-dipolar cycloaddition reactions of N-phenacylphenanthrolinium bromides or N-ethoxycarbonylmethylene phenanthrolinium bromide with various nitrostyrenes in acetonitrile at room temperature in the presence of triethylamine.

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Authors and Affiliations

  1. Analysis and Test Center, Yangzhou University, Yangzhou, 225002, P. R. China

    Zhen-ming Liu

  2. College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, 225002, P. R. China

    Jun Fang & Chao-guo Yan

Authors
  1. Zhen-ming Liu
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  2. Jun Fang
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  3. Chao-guo Yan
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Corresponding author

Correspondence to Chao-guo Yan.

Additional information

Supported by the National Natural Science Foundation of China(No. 21172189) and the Priority Academic Program Development of Jiangsu Higher Education Institutions, China.

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Liu, Zm., Fang, J. & Yan, Cg. Diastereoselective synthesis of 1,10-dihydropyrrolo[1,2-a][1,10]phenanthroline derivatives via 1,3-dipolar cycloaddition reaction. Chem. Res. Chin. Univ. 29, 1089–1093 (2013). https://doi.org/10.1007/s40242-013-3224-2

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  • DOI: https://doi.org/10.1007/s40242-013-3224-2

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