Summary
Background
There are no studies based on a person-centered approach addressing sex-related differences in the characteristics of treatment-seeking patients with gambling disorder (GD). The main objective of the current study is to identify empirical clusters of GD based on several measures of the severity of gambling behavior, and considering the potential role of patient sex as a moderator.
Methods
An agglomerative hierarchical clustering method was applied to an adult sample of 512 treatment-seeking patients (473 men and 39 women) by using a combination of the Schwarz Bayesian Information Criterion and log-likelihood function.
Results
Three clusters were identified in the subsample of men: cluster M1 (low-mild gambling severity level, 9.1%), cluster M2 (moderate level, 60.9%), and cluster M3 (severe level, 30.0%). In the women subsample, two clusters emerged: cluster W1 (mild-moderate level, 64.1%), and cluster W2 (severe level, 35.9%). The most severe GD profiles were related to being single, multiple gambling preference for nonstrategic plus strategic games, early onset of the gambling activity, higher impulsivity levels, higher dysfunctional scores in the personality traits of harm avoidance, and self-directedness, and higher number of lifespan stressful life events (SLE). Differences between the empirical men and women clusters were found in different sociodemographic and clinical measurements.
Conclusions
Men and women have distinct profiles regarding gambling severity that can be identified by a clustering approach. The sociodemographic and clinical characterization of each cluster by sex may help to establish specific preventive and treatment interventions.
Zusammenfassung
Hintergrund
Es gibt keine Studien, die auf einem personenzentrierten Ansatz beruhen und sich mit geschlechtsspezifischen Unterschieden in den Merkmalen von behandlungssuchenden Patienten mit einer Glücksspielstörung (GD) befassen. Wesentliches Ziel der vorgestellten Studie ist es, empirische GD-Cluster zu identifizieren, die auf mehreren Messungen der Schwere des Spielverhaltens basieren und dabei die mögliche Rolle des Geschlechts als moderierenden Faktor berücksichtigen.
Methodik
An einer erwachsenen Stichprobe von 512 behandlungssuchenden Patienten (473 männliche, 39 weibliche) wurde eine agglomerierende hierarchische Clustering-Methode angewendet unter Einsatz einer Kombination aus dem Schwarz-Bayes-Kriterium und einer logarithmischen Wahrscheinlichkeitsfunktion.
Ergebnisse
In der Unterstichprobe der Männer wurden 3 Cluster identifiziert: Cluster M1 (niedrig-mildes Niveau der Spielauffälligkeit, 9,1%), Cluster M2 (moderates Niveau, 60,9%) und Cluster M3 (hohes Niveau, 30,0%). In der Unterstichprobe der Frauen ergaben sich 2 Cluster: Cluster W1 (mäßiges Niveau, 64,1%) und Cluster W2 (hohes Niveau, 35,9%). Die gravierendsten GD-Profile bezogen sich auf Einzel- und Mehrfachspielpräferenz für nichtstrategische und strategisch orientierte Spiele, frühes Einsetzen der Spielaktivität, höhere Impulsivitätsgrade, höhere dysfunktionale Werte bei den Persönlichkeitsmerkmalen Schadensvermeidung und Selbststeuerung sowie eine höhere Anzahl von belastenden Lebensereignissen (SLE). Unterschiede zwischen den empirischen Männer- und Frauen-Clustern wurden in verschiedenen soziodemographischen und klinischen Messungen gefunden.
Schlussfolgerungen
Männer und Frauen haben unterschiedliche Profile hinsichtlich der Spielauffälligkeit, die sich durch einen Clustering-Ansatz identifizieren lassen. Die soziodemographische und klinische Charakterisierung jedes Clusters nach Geschlecht kann dazu beitragen, spezifische Präventions- und Behandlungsmaßnahmen zu etablieren.
Similar content being viewed by others
References
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington D.C.: American Psychiatric Association; 2013.
Langham E, Thorne H, Browne M, Donaldson P, Rose J, Rockloff M. Understanding gambling related harm: a proposed definition, conceptual framework, and taxonomy of harms. BMC Public Health. 2016;16(1):80.
Latvala T, Lintonen T, Konu A. Public health effects of gambling—debate on a conceptual model. BMC Public Health. 2019;19(1):1077.
Elton-Marshall T, Wijesingha R, Sendzik T, Mock SE, van der Maas M, McCready J, et al. Marital Status and Problem Gambling among Older Adults: An Examination of Social Context and Social Motivations. Can J Aging. 2018;37(3):318–32.
Calado F, Griffiths MD. Problem gambling worldwide: An update and systematic review of empirical research (2000–2015). J Behav Addict. 2016;5(4):592–613.
The-Lancet. Problem gambling is a public health concern. Vol. 390, Lancet (London, England). England; 2017. p. 913.
van Schalkwyk MCI, Cassidy R, McKee M, Petticrew M. Gambling control: in support of a public health response to gambling. Lancet. 2019;393(10182):1680–1.
Wardle H, Reith G, Langham E, Rogers RD. Gambling and public health: we need policy action to prevent harm. BMJ. 2019;365:l1807.
Calado F, Alexandre J, Griffiths MD. Prevalence of adolescent problem gambling: a systematic review of recent research. J Gambl Stud. 2017;33(2):397–424. https://doi.org/10.1007/s10899-016-9627-5.
Saunders JB, Hao W, Long J, King DL, Mann K, Fauth-Bühler M, et al. Gaming disorder: Its delineation as an important condition for diagnosis, management, and prevention. J Behav Addict. 2017;6(3):271–9. https://doi.org/10.1556/2006.6.2017.039.
McCarthy S, Thomas SL, Bellringer ME, Cassidy R. Women and gambling-related harm: a narrative literature review and implications for research, policy, and practice. Harm Reduct J. 2019;16(1):18.
Baxter A, Salmon C, Dufresne K, Carasco-Lee A, Matheson FI. Gender differences in felt stigma and barriers to help-seeking for problem gambling. Addict Behav. 2016;3:1–8.
Wong G, Zane N, Saw A, Chan AKK. Examining gender differences for gambling engagement and gambling problems among emerging adults. J Gambl Stud. 2013;29(2):171–89.
Hing N, Russell A, Tolchard B, Nower L. Risk factors for gambling problems: an analysis by gender. J Gambl Stud. 2016;32(2):511–34.
Valero-Solis S, Granero R, Fernández-Aranda F, Steward T, Mestre-Bach G, Mallorquí-Bagué N, et al. The contribution of sex, personality traits, age of onset and disorder duration to behavioral addictions. Front Psychiatry. 2018;9:497. https://doi.org/10.3389/fpsyt.2018.00497/full.
Krueger RF. The structure of common mental disorders. Arch Gen Psychiatry. 1999;56(10):921–6.
Oleski J, Cox BJ, Clara I, Hills A. Pathological gambling and the structure of common mental disorders. J Nerv Ment Dis. 2011;199(12):956–60.
Echeburúa E, González-Ortega I, de Corral P, Polo-López R. Clinical gender differences among adult pathological gamblers seeking treatment. J Gambl Stud. 2011;27(2):215–27.
Granero R, Penelo E, Martínez-Giménez R, Álvarez-Moya E, Gómez-Peña M, Aymamí MN, et al. Sex differences among treatment-seeking adult pathologic gamblers. Compr Psychiatry. 2009;50(2):173–80.
Khanbhai Y, Smith D, Battersby M. Gender by preferred gambling activity in treatment seeking problem gamblers: a comparison of subgroup characteristics and treatment outcomes. J Gambl Stud. 2017;33(1):99–113. https://doi.org/10.1007/s10899-016-9614-x.
Ronzitti S, Lutri V, Smith N, Clerici M, Bowden-Jones H. Gender differences in treatment-seeking British pathological gamblers. J Behav Addict. 2016;5(2):231–8.
Asendorpf JB. Typeness of personality profiles: A continuous person-centred approach to personality data. Eur J Pers. 2006;20:83–106.
Romild U, Svensson J, Volberg R. A gender perspective on gambling clusters in Sweden using longitudinal data. NAD Nord Stud Alcohol Drugs. 2016;33:43–60.
Granero R, Fernández-Aranda F, Mestre-Bach G, Steward T, García-Caro B, Prever F, et al. Clustering of treatment-seeking women with gambling disorder. J Behav Addict. 2018;7(3):770–80. https://doi.org/10.1556/2006.7.2018.93.
Stinchfield R. Reliability, validity, and classification accuracy of a measure of DSM-IV diagnostic criteria for pathological gambling. Am J Psychiatry. 2003;160(1):180–2.
Jiménez-Murcia S, Stinchfield R, Álvarez-Moya E, Jaurrieta N, Bueno B, Granero R, et al. Reliability, validity, and classification accuracy of a spanish translation of a measure of DSM-IV diagnostic criteria for pathological gambling. J Gambl Stud. 2009;25(1):93–104.
Raylu N, Oei TPS. The Gambling Related Cognitions Scale (GRCS): development, confirmatory factor validation and psychometric properties. Addiction. 2004;99(6):757–69.
Whiteside SP, Lynam DR, Miller JD, Reynolds SK. Validation of the UPPS impulsive behaviour scale: a four-factor model of impulsivity. Eur J Pers. 2005;19(7):559–74.
Verdejo-Garcia A, Lozano O, Moya M, Alcazar MA, Perez-Garcia M. Psychometric properties of a Spanish version of the UPPS‑P impulsive behavior scale: reliability, validity and association with trait and cognitive impulsivity. J Pers Assess. 2010;92(1):70–7.
Cloninger CR, Przybeck TR, Syrakic DM, Wetzel RD. The Temperament and Character Inventory (TCI). A guide to its development and use. St. Louis: Washington University, Center for Psychobiology of Personality; 1994.
Gutiérrez-Zotes JA, Bayón C, Montserrat C, Valero J, Labad A, Cloninger CR, et al. Temperament and Character Inventory Revised (TCI-R). Standardization and normative data in a general population sample. Actas Españolas Psiquiatr. 2004;32(1):8–15.
Kroenke K, Spitzer RL. The PHQ-9: A new depression diagnostic and severity measure. Psychiatr Ann. 2002;32:509–21.
Moriarty AS, Gilbody S, McMillan D, Manea L. Screening and case finding for major depressive disorder using the Patient Health Questionnaire (PHQ-9): a meta-analysis. Gen Hosp Psychiatry. 2015;37(6):567–76.
Hollingshead AB. Four factor index of social status. Yale J Soc. 2011;8:21–51.
Nylund KL, Asparouhov T, Muthén BO. Deciding on the number of classes in latent class analysis and growth mixture modeling: A Monte Carlo simulation study. Struct Equ Model. 2007;14(4):535–69.
Rousseeuw PJ. Silhouettes: a graphical aid to the interpretation and validation of cluster analysis. J Comput Appl Math. 1987;20:53–65.
Finner H. On a monotonicity problem in step-down multiple test procedures. J Am Stat Assoc. 1993;88:920–3.
Kelley K, Preacher KJ. On effect size. Psychol Methods. 2012;17(2):137–52.
Welte JW, Barnes GM, Wieczorek WF, Tidwell M‑C, Parker J. Gambling participation in the U.S.—results from a national survey. J Gambl Stud. 2002;18(4):313–37.
Dowling NA, Merkouris SS, Greenwood CJ, Oldenhof E, Toumbourou JW, Youssef GJ. Early risk and protective factors for problem gambling: a systematic review and meta-analysis of longitudinal studies. Clin Psychol Rev. 2017;51:109–24.
LaPlante DA, Nelson SE, Gray HM. Breadth and depth involvement: Understanding Internet gambling involvement and its relationship to gambling problems. Psychol Addict Behav. 2014;28(2):396–403.
Phillips JG, Ogeil R, Chow Y‑W, Blaszczynski A. Gambling involvement and increased risk of gambling problems. J Gambl Stud. 2013;29(4):601–11.
Holtgraves T. Gambling, gambling activities, and problem gambling. Psychol Addict Behav. 2009;23(2):295–302.
Castrén S, Heiskanen M, Salonen AH. Trends in gambling participation and gambling severity among Finnish men and women: cross-sectional population surveys in 2007, 2010 and 2015. BMJOpen. 2018;8(8):e22129. Aug.
Jiménez-Murcia S, Álvarez-Moya EM, Stinchfield R, Fernández-Aranda F, Granero R, Aymamí N, et al. Age of onset in pathological gambling: clinical, therapeutic and personality correlates. J Gambl Stud. 2010;26(2):235–48. https://doi.org/10.1007/s10899-009-9175-3.
Burge AN, Pietrzak RH, Molina CA, Petry NM. Age of gambling initiation and severity of gambling and health problems among older adult problem gamblers. Psychiatr Serv. 2004;55(12):1437–9.
Subramaniam M, Abdin E, Shahwan S, Vaingankar JA, Picco L, Browning CJ, et al. Culture and age influences upon gambling and problem gambling. Addict Behav. 2015;1:57–63.
Rahman AS, Pilver CE, Desai RA, Steinberg MA, Rugle L, Krishnan-Sarin S, et al. The relationship between age of gambling onset and adolescent problematic gambling severity. J Psychiatr Res. 2012;46(5):675–83.
Brunborg GS, Hanss D, Mentzoni RA, Molde H, Pallesen S. Problem gambling and the five-factor model of personality: a large population-based study. Addiction. 2016;111(8):1428–35.
Forbush KT, Shaw M, Graeber MA, Hovick L, Meyer VJ, Moser DJ, et al. Neuropsychological characteristics and personality traits in pathological gambling. CNS Sectr. 2008;13(4):306–15.
Cloninger CR, Svrakic DM, Przybeck TR. A psychobiological model of temperament and character. Arch Gen Psychiatry. 1993;50(12):975–90.
Moragas L, Granero R, Stinchfield R, Fernández-Aranda F, Fröberg F, Aymamí N, et al. Comparative analysis of distinct phenotypes in gambling disorder based on gambling preferences. BMC Psychiatry. 2015;15(1):86.
Jiménez-Murcia S, Granero R, Fernández-Aranda F, Stinchfield R, Tremblay J, Steward T, et al. Phenotypes in Gambling Disorder Using Sociodemographic and Clinical Clustering Analysis: An Unidentified New Subtype? Front Psychiatry. 2019;10:173. https://doi.org/10.3389/fpsyt.2019.00173/full.
Nordin C, Nylander P‑O. Temperament and character in pathological gambling. J Gambl Stud. 2007;23(2):113–20.
Kim HR, Kim SM, Han DH, Lee YS. Protective and risk factors for depressive mood and anxiety against occupational stress: examining temperament character and coping strategy among civil servants. Arch Environ Occup Health. 2019; https://doi.org/10.1080/19338244.2019.1666789.
Ciccarelli M, Griffiths MD, Nigro G, Cosenza M. Decision making, cognitive distortions and emotional distress: a comparison between pathological gamblers and healthy controls. J Behav Ther Exp Psychiatry. 2017;54:204–10.
Tavares H, Zilberman ML, Hodgins DC, el-Guebaly N. Comparison of craving between pathological gamblers and alcoholics. Alcohol Clin Exp Res. 2005;29(8):1427–31.
Yau YHC, Crowley MJ, Mayes LC, Potenza MN. Are Internet use and video-game-playing addictive behaviors? Biological, clinical and public health implications for youths and adults. Minerva Psichiatr. 2012;53(3):153–70.
Fontenelle LF, Oostermeijer S, Harrison BJ, Pantelis C, Yucel M. Obsessive-compulsive disorder, impulse control disorders and drug addiction: common features and potential treatments. Drugs. 2011;71(7):827–40.
Brevers D, Noel X. Pathological gambling and the loss of willpower: a neurocognitive perspective. Socioaffect Neurosci Psychol. 2013;3:21592.
Harris A, Griffiths MD. The impact of speed of play in gambling on psychological and behavioural factors: a critical review. J Gambl Stud. 2018;34(2):393–412.
Blanco C, Hasin DS, Petry N, Stinson FS, Grant BF. Sex differences in subclinical and DSM-IV pathological gambling: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Med. 2006;36(7):943–53.
Petry NM. A comparison of young, middle-aged, and older adult treatment-seeking pathological gamblers. Gerontologist. 2002;42(1):92–9.
Slutske WS, Piasecki TM, Deutsch AR, Statham DJ, Martin NG. Telescoping and gender differences in the time course of disordered gambling: evidence from a general population sample. Addiction. 2015;110(1):144–51.
Canale N, Rubaltelli E, Vieno A, Pittarello A, Billieux J. Impulsivity influences betting under stress in laboratory gambling. Sci Rep. 2017;7(1):10668.
Bergen AE, Newby-Clark IR, Brown A. Low trait self-control in problem gamblers: evidence from self-report and behavioral measures. J Gambl Stud. 2012;28(4):637–48.
Madeira SC, Oliveira AL. Biclustering algorithms for biological data analysis: a survey. IEEE/ACM Trans Comput Biol Bioinforma. 2004;1(1):24–45.
Helgeson ES, Liu Q, Chen G, Kosorok MR, Bair E. Biclustering via sparse clustering. Biometrics. 2020. https://doi.org/10.1111/biom.13136
Fineberg NA, Demetrovics Z, Stein DJ, Ioannidis K, Potenza MN, Grunblatt E, et al. Manifesto for a European research network into problematic usage of the internet. Eur Neuropsychopharmacol. 2018;28(11):1232–46.
Volberg RA. The future of gambling in the United Kingdom. BMJ. 2000;320:1556.
Álvarez-Moya EM, Jiménez-Murcia S, Aymamí MN, Gómez-Peña M, Granero R, Santamaría J, et al. Subtyping study of a pathological gamblers sample. Can J Psychiatry. 2010;55(8):498–506.
Wenzel HG, Dahl AA. Female pathological gamblers—A critical review of the clinical findings. Int J Ment Health Addict. 2009;7:190–202.
Stewart SH, Zack M, Collins P, Klein RM. Subtyping pathological gamblers on the basis of affective motivations for gambling: relations to gambling problems, drinking problems, and affective motivations for drinking. Psychol Addict Behav. 2008;22(2):257–68. https://doi.org/10.1037/0893-164X.22.2.257.
Funding
This manuscript and research were supported by grant from the Dirección General de Ordenación del Juego (DGOJ), Ministerio de Hacienda y Administraciones Públicas (RISCJPESP-2016). We thank the efforts of the following centers by contributing data recruited among their patients: ABAJ (Asociación Burgalesa Anónimo de Jugadores); ABLA (Associació Barcelonesa de Ludopatia i Addiccions); ACENCAS (Associació Catalana d’Addiccions socials); ACOGER (Asociación Cordobesa de Jugadores en Rehabilitación); ADAT (Asociación Dombenitense de Ayuda al Toxicómano); ALUJER (Asociación de Ludópatas Jienense en Rehabilitación); ASAJER (Asociación de Jugadores en Rehabilitación); Asociación Proyecto Hombre; AZAJER (Asociación Aragonesa de Jugadores de Azar); EL AZAR (Asociación de Jugadores en Recuperación); FAJER (Federación Andaluza de Asociaciones de Jugadores de Azar en Rehabilitación); FEJAR (Federación Española de Jugadores de Azar Rehabilitados); Fundación Acorde; Fundación Adsis; Fundación Salud y Comunidad; Institut Pere Mata; Jugadores Anónimos—Área 21; Jugadores Anónimos—España; Jugadores Anónimos—Grupo Arganda; JUGUESCA (Associació Juguesca Ludopatia); Oficina Registro de la DGOJ; PATIM (Prevención y Tratamiento de Drogodependencias y Otras Adicciones); Proyecto Amigó; Proyecto Hombre—La Rioja; Proyecto Hombre—Murcia; SEPD (Sociedad Española de Patología Dual, Dr. Ignacio Basurte); Unitat de Conductes Addictives (Hospital de la Santa Creu i Sant Pau); Unitat de Joc Patològic i Altres Adiccions Conductuals (Hospital Universitari de Bellvitge).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
S. Jiménez-Murcia, R. Granero, M. Giménez, A. del Pino-Gutiérrez, G. Mestre-Bach, T. Mena-Moreno, L. Moragas, M. Baño, J. Sánchez-González, M. de Gracia, I. Baenas-Soto, S. F. Contaldo, E. Valenciano-Mendoza, B. Mora-Maltas, H. López-González, J.M. Menchón, and F. Fernández-Aranda declare that they have no competing interests.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Jiménez-Murcia, S., Granero, R., Giménez, M. et al. Moderator effect of sex in the clustering of treatment-seeking patients with gambling problems. Neuropsychiatr 34, 116–129 (2020). https://doi.org/10.1007/s40211-020-00341-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40211-020-00341-1