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Correlation between drinking water fluoride and TSH hormone by ANNs and ANFIS

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Journal of Environmental Health Science and Engineering Aims and scope Submit manuscript

Abstract

Background

Artificial neural networks (ANNs) and adaptive neural-fuzzy Inference system (ANFIS) are the best solutions to finding the correlation between some water parameters and human hormones. The correlation between thyroid stimulating hormone (TSH) and drinking water fluoride studied by ANNS and ANFIS models in Yazd city.

Method

In this study, eighty people with thyroid gland disorder and 213 healthy people invited. Their thyroid hormones and fluoride drinking water analyzed.

Results

The result of ANFIS showed R2 = 0.81 for test and R2 = 0.85 for train in all cases and controls data. This results were R2 = 0.73 and R2 = 0.81 for ANNs respectively.

Conclusion

This models can be used as an alternative for show correlation between Drinking Water Fluoride and TSH Hormone and R2 = 0.85 gained from ANFIS was the best.

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Abbreviations

ANFIS:

Adaptive neural-fuzzy inference system

ANNS:

Artificial neural networks

NRMSE:

Normalized root-mean-square deviation

R2 :

R-squared

RMSE:

root-mean-squared error

T3:

Triiodothyronine

T4:

Thyroxin

Train GD:

Gradient descent

Train GDA:

Gradient descent with adaptive learning rate back propagation

Train GDX:

Variable Learning Rate Back propagation

Train LM:

Levenberg-Marquardt

Train SCG:

Scaled Conjugate Gradient

TSH:

Thyroid stimulating hormone

YaHS:

Yazd Healthy Study

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Acknowledgements

We acknowledge Yazd Healthy Study participants who gave us their time and drinking water samples.

Funding

This research was supported by Yazd University of Medical Sciences.

Author information

Authors and Affiliations

  1. Environmental Science and Technology Research Center, Department of Environmental Health Engineering, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Zohreh Kheradpisheh, Mehdi Mokhtari & Mohammad Hassan Ehrampoush

  2. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

    Amir Hossein Mahvi

  3. Center for Solid Waste Research, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran

    Amir Hossein Mahvi

  4. Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Masoud Mirzaei

  5. Department of Endocrinology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Reyhane Azizi

  6. Department of Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Hossein Fallahzadeh

Authors
  1. Zohreh Kheradpisheh
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  2. Amir Hossein Mahvi
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  4. Mehdi Mokhtari
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  5. Reyhane Azizi
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  7. Mohammad Hassan Ehrampoush
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Contributions

ZKH and MHE was the main investigator, collected the data, MM, MM and AHM supervised the study. MK and RA and HF were advisors of the study. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Amir Hossein Mahvi or Mohammad Hassan Ehrampoush.

Ethics declarations

This study is Compliance with Ethical Standards. This study funded by Environmental Science and Technology Research Center, Department of Environmental Health Engineering, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Ethical approval

Case and control people choses with their consent and have been informed about study and they invited for Thyroid hormones test. Their thyroid hormones analyze in Yazd Central Laboratory.

Competing interests

The authors declare that they have no competing interests.

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Kheradpisheh, Z., Mahvi, A.H., Mirzaei, M. et al. Correlation between drinking water fluoride and TSH hormone by ANNs and ANFIS. J Environ Health Sci Engineer 16, 11–18 (2018). https://doi.org/10.1007/s40201-018-0290-x

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  • DOI: https://doi.org/10.1007/s40201-018-0290-x

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