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Evaluating the effect of cold plasma on the healing of gingival wound

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Journal of Diabetes & Metabolic Disorders Aims and scope Submit manuscript

Abstract

Background

This is the first study that conducted to the effect of cold plasma on the healing of gingival wound in diabetic rabbits.

Material and method

Eighteen healthy rabbits is purched from pastor institute. The aloxan was injected to the rabbits. After induction of anesthesia the gum tissue is removed. The rabbits were treated by the plasma jet for 3, 5 and 10 days each day 30 s and they were considered histological.

Results and discussion

After 3 days the plasma jet treatment, the production of collagen and fibroblast and migration of epithelial cells is observed. As can be seen from the results after 5 days the cold plasma treatment the increase of neovascularation, collagen and inflammatory infiltration is seen in gum tissue. Formation of granulation tissue is seen after 10 days the plasma jet treatment.

Conclusion

The cold plasma treatment is an effective way for gingival wound treatment. Cold plasma treatment resulted in reduction of inflammatory phase and accelerates the recovery phase by increase neovascularation and collagen production.

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Authors and Affiliations

  1. Department of Veterinary Medicine, Tehran Azad University Science and Research Branch, Tehran, Iran

    Alireza Jahandideh & Hoda Porbagher

  2. Plasma Physics Research Center, Science and Research Branch, Islamic Azad University, Tehran, Iran

    Maryam Amini

  3. Diabetes Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Science, Tehran, Iran

    Mohammdreza Amini

Authors
  1. Alireza Jahandideh
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  2. Maryam Amini
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  3. Hoda Porbagher
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  4. Mohammdreza Amini
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Correspondence to Maryam Amini.

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Jahandideh, A., Amini, M., Porbagher, H. et al. Evaluating the effect of cold plasma on the healing of gingival wound. J Diabetes Metab Disord 20, 741–745 (2021). https://doi.org/10.1007/s40200-021-00810-6

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  • DOI: https://doi.org/10.1007/s40200-021-00810-6

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