Abstract
Metal-oxide-based nanostructure has got a significant interest for anticorrosion, antioxidant, and antibacterial applications. Herein, ZnO nanoparticles (NPs) and nanoneedles (NNs) are prepared by hydrothermal synthesis and used for antibacterial and antioxidant properties. The scanning electron microscopy (SEM), transmission electron microcopy (TEM), X-ray diffraction (XRD) and UV–visible Spectroscopy are used to characterize the ZnO-based nanostructures. The ZnO NNs exhibit excellent antibacterial properties against a strain of Gram-positive and Gram-negative bacterium of (18 and 16 nm) zone of inhibition (ZOI) compared to ZnO NPs (10 and 12 mm ZOI), respectively. Moreover, their scavenging against 2,2-diphenyl-1-picryhydrazyl free radical is investigated. The ZnO NNs show the highest antioxidant activity (~ 94%) compared to ZnO NP (~ 46%). We believe this study is aims to be significant in various bio-medical industries regarding new structures development as well as antibacterial and antioxidant studies.
Graphical abstract
References
Desselberger, U.: Emerging and re-emerging infectious diseases. J. Infect. 40(1), 3–15 (2000)
Jones, N., Ray, B., Ranjit, K.T., Manna, A.C.: Antibacterial activity of ZnO nanoparticle suspensions on a board spectrum of microorganisms. FEMS Microbiol. Lett. 279, 71–76 (2008)
Hajipour, M.J., Fromm, K.M., Ashkarran, A.A., de Aberasturi, D.J., de Larramendi, I.R., Rojo, T., Serpooshan, V., Parak, W.J., M.: Mahmoudi antibacterial properties of nanoparticles. Trends Biotechnol 30(10), 499–511 (2012)
Iqbal, M., Ibrar, A., Ali, A., Rehman, F., Jatoi, A.H., Jatoi, W.B., Phulpoto, S., Thebo, K.H.: Facile synthesis of Zn-doped CdS nanowires with efficient photocatalyt. Environ. Technol. (2002). https://doi.org/10.1080/09593330.2020.1850880
Nahyoon, N.A., Liu, L., Rabe, K., Thebo, K.H., Yuan, L., Sun, J., Yang, F.: Significant photocatalytic degradation and electricity generation in the photocatalytic fuel cell (PFC) using novel anodic nanocomposite of Fe, graphene oxide, and titanium phosphate. Electrochim. Acta 271, 41–48 (2018)
Iqbal, M., Ali, A., Nahyoon, N.A., Majeed, A., Pothu, R., Phulpoto, S., Thebo, K.H.: Photocatalytic degradation of organic pollutant with nanosized cadmium sulfide. Mater. Sci. Energy Technol. 2, 41–45 (2019)
Iqbal, M., Thebo, A.A., Jatoi, W.B., Tabassum, M.T., Thebo, K.H., Mohsin, M.A., Jatoi, A.H., Shah, I.: Facile synthesis of Cr doped hierarchical ZnO nano-structures for enhanced photovoltaic performance. Inorg. Chem. Commun. 116, 10790 (2020)
Khan, J., Ullah, H., Sajjad, M., Ali, A., Thebo, K.H.: Synthesis, characterization and electrochemical performance of cobalt fluoride nanoparticles by reverse micro-emulsion method. Inorg. Chem. Commun. 98, 132–140 (2018)
Iqbal, M., Thebo, A.A., Ahmed, K.S., Rana, F.M., Khan, J., Khan, K., Thebo, K.H.: Synthesis and characterization of transition metals doped CuO nanostructure and their application in hybrid bulk heterojunction solar cells. SN Sci. 1, 647 (2019)
Khan, J., Ullah, H., Sajjad, M., Jatoi, W.B., Ali, A., Khan, K., Thebo, K.H.: Controlled synthesis of ammonium manganese tri-fluoride nanoparticles with enhanced electrochemical performance. Mater. Res. Express 6(7), 07507 (2019)
Iqbal, M., Thebo, A.A., Shah, A.H., Iqbal, A., Thebo, K.H., Phulpoto, S., Mohsin, M.A.: Influence of transition metal doping on the photocatalytic activity and solar cell efficiency of CuO nanowires. Inorg. Chem. Commun. 76, 71–76 (2017)
Dey, P.C., Ingti, B., Bhattacharjee, A., Choudhury, M.D., Das, R., Nath, S.S.: Enhancement of antibacterial activity of synthesized ligand-free CdS nanocrystals due to silver doping. J Basic Microbiol. 61(1), 27–36 (2021)
Dey, P.C., Nath, P., Maiti, D., Das, R.: Antibacterial activity of MPA-capped CdTe and Ag-doped CdTe nanocrystals: showing different activity against gram-positive and gram-negative bacteria. Chem. Pap. 74, 3409–3421 (2020)
Willner, M.R., Vikesland, P.J.: Nanomaterial enabled sensors for environmental contaminants. J. Nanobiotechnol. 16(95), 1–16 (2018)
Sanvicens, N., Pastells, C., Pascual, N., Marco, M.-P.: Nanoparticle-based biosensor for detection of pathogenic bacteria. Trends Anal. Chem. 28(11), 1243–1252 (2009)
Liu, Y., He, L., Mustapha, A., Li, H., Hu, Z.Q., Lin, M.: Antibacterial activities of zinc oxide nanoparticles against echerichia coli O157:H7. J. Appl. Microbiol. 107, 1193–1201 (2009)
Padmavathy, N., Vijayaraghavan, R.: Enhanced bioactivity of ZnO nanoparticles—an antimicrobial study. Sci. Technol. Adv. Mater. 9(3), 035004 (2008)
Siddiqi, K.S., Rahman, A., Husen, A.: Properties of zinc oxide nanoparticles and their activity against microbes. Nanoscale Res. Lett. 13, 141–153 (2018)
Brayner, R., Ferrari-Iliou, R., Brivois, N., Djediat, S., Benedetti, M.F., Fiévet, F.: Toxicology impact studies based on escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano. Lett. 6(4), 866–870 (2006)
Sirelkhatim, A., Mahmud, S., Seeni, A., Kaus, N.H.M., Ann, L.C., Bakhori, S.K.M., Hasan, H., Mohamad, D.: Review on zinc oxide nanoparticles: antibacterial activity and toxicity mechanism. Nano-Micro. Lett. 7, 219–242 (2015)
Das, D., Nath, B.C., Phukon, P., Kalita, A., Dolui, S.K.: Synthesis of ZnO nanoparticles and evaluation of antioxidant and cytotoxic activity. Coll. Surf. B Biointerf. 111, 556–560 (2013)
Zhang, Z.Y., Xiong, H.M.: Photoluminescent ZnO nanoparticles and their biological applications. Materials 8(6), 3101–3127 (2015)
Shi, L.E., Li, Z.H., Zheng, W., Zhao, Y.F., Jin, Y.F., Tang, Z.X.: Synthesis, antibacterial activity, antibacterial mechanism and food applications of ZnO nanoparticles: a review. Food Addit. Contam. Part A 31(2), 173–186 (2014)
Jiang, Y., Zhang, L., Wen, D., Ding, Y.: Role of physical and chemical interactions in the antibacterial behavior of ZnO nanoparticles against E. coli. Mater. Sci. Eng. C 69, 1361–1366 (2016)
Dutta, R.K., Nenavathu, B.P., Gangishetty, M.K., Reddy, A.V.: Antibacterial effect of chronic exposure of low concentration ZnO nanoparticles on E. coli. J. Environ. Sci. Health Part A 48(8), 871–878 (2013)
Alwan, R.M., Kadhim, Q.A., Sahan, K.M., Ali, R.A., Mahdi, R.J., Kassim, N.A., Jassim, A.N.: Synthesis of Zinc Oxide Nanoparticles via Sol-Gel Route and Their Characterization. Nanosci. Nanotechnol. 5(1), 1–6 (2015)
Darezereshki, E., Alizadeh, M., Bakhtiari, F., Schaffie, M., Ranjbard, M.: A novel thermal decomposition method for the synthesis of ZnO nanoparticles from low concentration ZnSO4 solutions. Appl. Clay Sci. 54, 107–111 (2011)
Raoufi, D.: Synthesis and microstructural properties of ZnO nanoparticles prepared by precipitation method. Renew. Energy 50, 932–937 (2013)
Vafaee, M., Ghamsari, M.S.: Preparation and characterization of ZnO nanoparticles by a novel sol-gel route. Mater. Lett. 61, 3265–3268 (2007)
Znaidi, L.: Sol-gel-deposited ZnO Thin Films: a Review. Mater. Sci. Eng. B 174, 18–30 (2010)
Aneesh, P.M., Vanaja, K.A., Jayaraj, M.K.: Synthesis of ZnO nanoparticles by hydrothermal method. Nanophotonic Mater. 6639, 66390J (2007)
Zhou, Qu., Chen, W., Lingna, Xu., Peng, S.: Hydrothermal synthesis of various hierarchical ZnO nanostructures and their methane sensing properties. Sensors 13, 6171–6182 (2013)
Ahmad, W., Shams, S., Wei, Y., Yuan, Q., Khan, U., Khan, M.S., Rahman, A.U., Iqbal, M.: Appl. Nanosci. 10, 1191–1204 (2019)
Jiang, I.Y., Wu, X.L., Guo, Y.G.: SnO2-based hierarchical nanomicrostrctures facile synthesis and their application in gas sensors and lithium-ion batteries. J. Phys. Chem. C 113, 14213–14219 (2009)
Li, Z., Xiong, Y., Xie, Y.: Selected-control synthesis of ZnO nanowires and nanorods via a PEG-assisted route. Inorg. Chem. 42, 8105–8109 (2003)
Yin, Y.X., Jiang, L.Y., Wan, L.J.: Polyethylene glycol-directed SnO2 anaowires for enhanced gas –sensing properties. Nanoscales 3, 1802–1806 (2011)
Chaturvedi, G., Kaur, A.: Sushil kumar kansal, cds-decorated MIL-53(Fe) microrods with enhanced visible light photocatalytic performance for the degradation of ketorolac tromethamine and mechanism insight. J. Phys. Chem. C 123(27), 16857–16867 (2019)
Gupta, M., Tomar, R.S., Kaushik, S., Mishra, R.K., Sharma, D.: Effective antimicrobial activity of green ZnO nano particles of catharanthus roseus. Front. Microbiol. (2018). https://doi.org/10.3389/fmicb.2018.02030/full
Kelly, K., Havrilla, C.M., Brady, T.C., Abramo, K.H., Levin, E.D.: Oxidative stress in toxicology: established mammalian and emerging piscine model systems. Environ. Health Perspect. 106(7), 375–384 (1998)
Xie, Y., He, Y., Irwin, P.L., Jin, T., Shi, X.: Antibacterial activity and mechanism of action of zinc oxide nanoparticles against Campylobacter jejuni. Appl. Environ. Microbiol. 77(7), 2325–2331 (2021)
Yang, H., Liu, C., Yang, D., Zhang, H., Xi, Z.: Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition. J. Appl. Toxicol. 29(1), 69–78 (2009)
Acknowledgements
Authors are also thankful for technical and research support from University of Haripur, Pakistan, National University of Science and Technology (NUST), Pakistan, Sukkur IBA University, and University of Chinese Academy of Science (UCAS), China.
Funding
This research is financially supported by the Higher Education Commission (HEC), Pakistan for Project No. 399/IPFP-II(Batch-1)/SRGP/NAHE/HEC/2020/23).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Conflict of interest
The author (s) reported no potential conflict of interest related to this work.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Iqbal, M., Ibrar, A., Ali, A. et al. Facile synthesis of zinc oxide nanostructures and their antibacterial and antioxidant properties. Int Nano Lett 12, 205–213 (2022). https://doi.org/10.1007/s40089-022-00370-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40089-022-00370-4