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Studies on Fragrance Delivery from Inorganic Nanocontainers: Encapsulation, Release and Modeling Studies

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Abstract

The present work deals with encapsulation of fragrance molecule in inorganic nanocontainers substrate and investigation of its prolonged release at different pH condition. The nanocontainers used were aluminosilicate clay (Halloysite) having cylindrical shape with outside diameter in the range of 30–50 nm, 15 nm lumen and length equal to 800 ± 300 nm. Rosewater absolute was used as a sample fragrance for loading in nanocontainer and delivery purpose. The fragrance loaded nanocontainers were coated with a thin layer of polyelectrolyte i.e. Polyacrylic Acid (PAA). The structural characteristics of prepared nanocontainers were determined by using Fourier Transform Intra-red Spectroscopy (FTIR), Thermal Gravimetric Analysis (TGA) and UV spectroscopy analysis. Release of fragrance molecules in the aqueous medium was monitored for 24 h. The fragrance release was found to be responsive as the amount of fragrance release increases with increase in pH value from 3 to 7. Fragrance release has been studied by using various permeation kinetic models such as zero order, first order, Hixson–Crowell, Higuchi, Korsmeyer–Peppas and Hopfenberg models. Korsemyer–Peppas shows the best fit (R2 = 0.9544) compared to other kinetic model for the release of fragrance from nanocontainers.

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Authors and Affiliations

  1. University Department of Chemical Technology, North Maharashtra University, Jalgaon, 425001, Maharashtra, India

    Shailesh Adinath Ghodke & Satyendra Mishra

  2. Department of Chemical Engineering, National Institute of Technology, Warangal, 506004, Andhra Pradesh, India

    Shirish Hari Sonawane

  3. Department of Chemical Engineering, Laxminarayan Institute of Technology, Nagpur, 440033, Maharashtra, India

    Bharat Apparao Bhanvase

  4. Department of Biotechnology, Sinhgad College of Engineering, Pune, 411041, Maharashtra, India

    Kalpana Shrikant Joshi

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  1. Shailesh Adinath Ghodke
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Correspondence to Shirish Hari Sonawane.

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Ghodke, S.A., Sonawane, S.H., Bhanvase, B.A. et al. Studies on Fragrance Delivery from Inorganic Nanocontainers: Encapsulation, Release and Modeling Studies. J. Inst. Eng. India Ser. E 96, 45–53 (2015). https://doi.org/10.1007/s40034-015-0059-z

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