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Protective Effect of Quercetin on Haematology and Flesh Quality in Labeo rohita Against Aflatoxin B1

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Abstract

The present study evaluates quercetin’s competitive interaction with aflatoxin B1 by testing its effects on haematology and flesh quality in rohu (Labeo rohita) for 90 days. The fingerlings were divided into five groups (D1, negative control), 100 ppb AFB1 (D2, positive control), 25 ppb AFB1 + 200 mg QC (D3), 50 ppb AFB1 + 200 mg QC (D4) and 100 ppb AFB1 + 200 mg QC (D5). The study was carried out in fibre-reinforced plastic pools with three replicates for each group. The results showed that diet supplementation of D3 led to a significant improvement in the tested haematological indices and in the flesh quality. Overall results suggest that dietary supplementation of QC could somehow positively influence the health status of L. rohita fingerlings and help to manage or counteract aflatoxin toxicity at some level and hence could be an important bioactive flavonoid for sustainability and behave as a strong antioxidant.

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Acknowledgements

The authors express their gratitude to the Dean, College of Fisheries, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, Punjab, India, for providing the field and laboratory facilities to perform the research.

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Authors and Affiliations

  1. Department of Aquaculture, College of Fisheries, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, 141004, India

    Deepa Bhatt, Abhed Pandey & Sachin Onkar Khairnar

  2. Department of Inland Fisheries, ZAHRS, Keladi Shivappa Nayaka University of Agricultural and Horticultural Sciences, Navile, Shivamogga, Karnataka, 577201, India

    Shanthanagouda A. Holeyappa

  3. Department of Animal Nutrition, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, 141004, India

    Jaspal Singh Hundal

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  1. Deepa Bhatt
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  2. Abhed Pandey
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  3. Shanthanagouda A. Holeyappa
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  4. Jaspal Singh Hundal
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  5. Sachin Onkar Khairnar
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Correspondence to Deepa Bhatt.

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Significant Statement: In tropical countries, aflatoxins are of great concern because they contaminate grains and seeds used as feed ingredients. Therefore, the present investigation was carried out to evaluate potential protective effects of quercetin (contain flavonoids) against the destructive effects of AFB1 on the haematology and flesh quality of L. rohita.

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Bhatt, D., Pandey, A., Holeyappa, S.A. et al. Protective Effect of Quercetin on Haematology and Flesh Quality in Labeo rohita Against Aflatoxin B1. Natl. Acad. Sci. Lett. 47, 133–137 (2024). https://doi.org/10.1007/s40009-023-01333-9

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  • DOI: https://doi.org/10.1007/s40009-023-01333-9

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