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Multicentric Castleman’s disease as a cause for unclear febrile episodes in a 55-year-old HIV-infected man

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Abstract

Our case illustrates the difficulties involved in diagnosing multicentric Castleman’s disease (MCD) in a human immunodeficiency virus-infected man with febrile episodes and malaise. In the absence of well-established treatment protocols, we have chosen a new treatment algorithm with rituximab, etoposide, and valganciclovir, which led to the remission of clinical symptoms. Yet, we advocate focused exploration for MCD in immunosuppressed patients with unclear febrile episodes, as recent advances in treatment are promising.

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Authors and Affiliations

  1. Department of Internal Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland

    H. Lederer

  2. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland

    Y. Achermann & J. Fehr

  3. Department of Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland

    M. Tinguely

  4. Department of Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland

    F. Stenner

Authors
  1. H. Lederer
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  2. Y. Achermann
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  3. M. Tinguely
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  4. F. Stenner
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  5. J. Fehr
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Corresponding author

Correspondence to J. Fehr.

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Lederer, H., Achermann, Y., Tinguely, M. et al. Multicentric Castleman’s disease as a cause for unclear febrile episodes in a 55-year-old HIV-infected man. Infection 40, 203–205 (2012). https://doi.org/10.1007/s15010-011-0174-9

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  • DOI: https://doi.org/10.1007/s15010-011-0174-9

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