Abstract.
Background: Viral hepatitis is characterized by special clinical, biochemical and serological findings. This study was planned to determine the seroprevalence, epidemiological characteristics and clinical and biochemical findings of hepatitis A virus (HAV) and hepatitis E virus (HEV) infections during an outbreak of jaundice.
Materials and Methods: 340 children aged 5–16 years were included. Clinical findings and alanine aminotransferase (ALT) levels were documented. Anti-HAV IgG and IgM in addition to anti-HEV IgG and IgM were determined by microELISA.
Results: Clinical findings, high levels of ALT, anti-HAV IgM and IgG, anti-HEV IgM and IgG were present in 6%, 23%, 17%, 100%, 7% and 9% of cases, respectively. The relationship between ALT levels and anti-HAV or anti-HEV IgM seropositivity was significant (p ≤ 0.0001).
Conclusion: HAV and HEV infection were both caused by a contaminated water supply.
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Received: September 21, 2001 · Revision accepted: April 23, 2002
RID="*"
ID="*"This study was presented as a poster at 11th European Congress of Clinical Microbiology and Infectious Diseases, Istanbul, Turkey, April 1–4, 2001.
A. R. Örmeci (corresponding author)
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Yayli, G., Kiliç, S. & Örmeci, A. Hepatitis Agents with Enteric Transmission – An Epidemiological Analysis. Infection 30, 334–337 (2002). https://doi.org/10.1007/s15010-002-2123-0
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DOI: https://doi.org/10.1007/s15010-002-2123-0