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Ultrasound-assisted multi-component synthesis of indazolophthalazine derivatives

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Abstract

An efficient multi-component synthesis of indazolophthalazine derivatives through the reaction of phthalhydrazide, 2-hydroxynaphthalene-1,4-dione or 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione and active carbonyl compounds under ultrasonic irradiation is reported. This chemistry provides an efficient and promising synthetic strategy to diversity-oriented construction of the indazolophthalazine skeleton with potential biological activities.

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Acknowledgments

We gratefully acknowledge financial support from the Research Council of Shahid Beheshti University.

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Authors and Affiliations

  1. Department of Chemistry, Shahid Beheshti University, General Campus, 1983963113, Tehran, Iran

    Milad Pedarpour Vajargahy, Minoo Dabiri & Ayoob Bazgir

  2. Department of Chemistry, University of New Brunswick, P. O. Box 4400, Fredricton, NB, E3B 5A3, Canada

    David MaGee

Authors
  1. Milad Pedarpour Vajargahy
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  2. Minoo Dabiri
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  3. David MaGee
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  4. Ayoob Bazgir
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Correspondence to Ayoob Bazgir.

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Vajargahy, M.P., Dabiri, M., MaGee, D. et al. Ultrasound-assisted multi-component synthesis of indazolophthalazine derivatives. J IRAN CHEM SOC 12, 1613–1621 (2015). https://doi.org/10.1007/s13738-015-0634-8

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  • DOI: https://doi.org/10.1007/s13738-015-0634-8

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