Abstract
This review explores the natural products of seagrass that are to be exploited for their bioactive potential. Beside from portraying the presence of a wide array of secondary compounds such as phenols, flavonoids, sterols and lipids from different seagrass species, the focus is on novel natural products projecting towards their biological applications. Though there are a significant number of reports on the abundance of secondary metabolites from seagrass and their bioactive derivatives, only a small number of reports explore their functional and defensive characteristics. Efforts have been made to collate the available information on seagrass natural products and clarify their function and metabolic pathway’s. It is emphasized that metabolic profiling of seagrass should be extensively progressed to obtain a deeper knowledge about the specific roles of each natural product. The investigation of seagrass natural products for their bioactive potential would most likely result in the detection of surprising and unexpected novel chemical structures and clinical leads that may be useful to mankind.
Article PDF
Similar content being viewed by others
References
Heglmeier, A.; Zidorn, C. Biochem. Syst. Ecol.2010, 38, 964–970.
Iriti, M.; Faoro, F. Curr. Top. Nutrac. Res.2004, 2, 47–95.
Papenbrock, J. ISRN Bot.2012, Doi: 10.5402/2012/103892.
Herrmann, K. M. Plant Physiol.1995, 107, 7–12.
Wilson, J. O.; Buchsbaum, R.; Valiella, I.; Swain, T. Mar. Ecol. Progr. Ser.1986, 29, 177–187.
Jaganath, I. B.; Crozier, A. Plant phenolics and Human health: Biochemistry, Nutrition and Pharmacology, John Wiley and Sons: Hoboken, New Jersey, 2010.
Vergeer, L. H. T.; Aarts, T. L.; De Groot, J. D, Aquat. Bot.1995, 52, 35–44.
Arnold, T. M.; Targett, N. M. J. Chem. Ecol.2002, 28, 1919–1934.
Higuchi, T.; Ito, Y.; Shlmada, M.; Kawamura, I. Phytochemistry 1967, 6, 1551–1556.
Hartley, R. D. Phytochemistry1973, 12, 661–665.
Athiperumalsami, T.; Kumar, V.; Jesudass, L. L. Bot. Mar.2008, 51, 269–277.
Pradheeba, M.; Dilipan, E.; Nobi, E. P.; Thangaradjou, T.; Sivakumar, K. Indian J. Geo-Mar. Sci.2011, 40(1), 105–111.
Kannan, R. R. R.; Arumugam, R.; Anantharaman, P. Curr. Bioact. Compd.2011, 7, 118–125.
Zapata, O.; McMillan, C. Aquat. Bot.1979, 7, 307–317.
Rajeshwari, M. Seagrass ecosystem of Coromandel coast. Final report submitted to Department of Chemical engineering, IIT Madras, 1990, p 167.
Ravn, H.; Pedersen, M. F.; Borum, J.; Andary, C.; Anthoni, U.; Christophen, C.; Nielsen, P. H. Ophelia1994, 40, 51–61.
Klap, V. A.; Hemminga, M. A.; Boon, J. J. Mar. Ecol. Progr. Ser.2000, 194, 1–11.
Dumay, O.; Costa, J.; Desjobert, J. M.; Pergent, G. Phytochemistry2004, 65, 3211–3220.
Kesraoui, O.; Marzouki, M. N.; Maugard, T.; Limam, F. Afr. J. Biotech.2011, 10 (6), 3176–3185.
Rotini, A.; Micheli, C.; Valiante, L.; Migliore, L. Open J. Ecol.2011, 1(2), 48–56.
Migliore, L.; Rotini, A.; Randazzo, D.; Albanese, N. N.; Giallongo, A. BMC Ecol.2007, 7, 1–6.
Dawes, C. J. Marine Botany. John Wiley and Sons: New York, 1998, pp.1–7.
Cariello, L.; Zanetti, L. Bot. Mar.1979, 922, 359–360.
Cuny, P.; Serve, L.; Jupin, H.; Boudouresque, C. F. Aquat. Bot.1995, 52, 237–242.
Agostini, S.; Desjobert, J. M.; Pergent, G. Phytochemistry1998, 48, 611–617.
Haznedaroglu, M. Z.; Zeybek, U. Pharm. Biol.2007, 45, 745–748.
Nusissier, G.; Rezzonico, B.; Dubois, M. G. Food Chem.2010, 120, 783–788.
Males, Z.; Plazibat, M. Hornem. Farm. Glas.2000, 56, 109–118.
Zimmerman, R. C.; Alberte, R. J.; Todd, S.; Crew, P. U.S. Patent 5384176, 1995.
Newby, B. M. Z.; Cutright, T.; Barrios, C. A.; Xu, Q. J. Coast. Technol. Res.2006, 3, 69–76.
Villa, F.; Albanese, D.; Giussani, B.; Stewart, P. S.; Daffonchio, D.; Cappitelli, F. Biofouling2010, 26, 739–752.
Stanley, M. S.; Callow, M. E.; Perry, R.; Alberte, R. S.; Smith, R.; Callow, J. A. Phytopathology2002, 92, 378–383.
Todd, J. S.; Zimmerman, R. C.; Crews, P.; Alberte, R. S.; Phytochemistry1993, 34(2), 401–404.
Achamlale, S.; Rezzonico, B.; Dubois, M. G. J. App. Phycol.2009, 21, 347–352.
Harborne, J. B.; Williams, C. A. Biochem. Syst. Ecol.1976, 37, 37–41.
McMillan, C.; Zapata, O.; Escobar, L. Aquat. Bot.1980, 8, 267–278.
Rowley, D. C.; Hansen, M. S. T.; Rhodes, D.; Sotriffer, C. A.; Ni, H.; McCammon, J. A.; Bushman, F. D.; Fenical, W. Bioorg. Med. Chem.2002, 10, 3619–3625.
Barron, D.; Varin, L.; Ibrahim, R. K.; Harborne, J. B.; Williams, C. A. Phytochemistry1988, 27, 2375–2395.
Takagi, M.; Funahashi, S.; Ohta, K.; Nakabayashi, T. Agric. Biol. Chem.1979, 43, 2417–2418.
Takagi, M.; Funahashi, S.; Ohta, K.; Nakabayashi, T. Agric. Biol. Chem.1979, 44, 3019–3020.
Buchsbaum, R. N.; Short, F. T.; Cheney, D. P. Aquat. Bot.1990, 37, 291–297.
Milkova, T.; Pelkova, R.; Christov, R.; Popov, S.; Dimitrova, K. S. Bot. Mar.1995, 38, 99–101.
Cannac, M.; Ferrat, L.; Pergent-Martini, C.; Pergent, G.; Pasqualini, V. Sci. Total Environ.2006, 370, 91–98.
Qi, S. H.; Zhang, S.; Qian, P. Y.; Wang, B. G. Bot. Mar.2008, 51, 441–447.
Meng, Y.; Krzysiak, A. J.; Durako, M. J.; Kunzelman, J. I.; Wright, J. L. C. Phytochemistry2008, 69, 2603–2608.
Bitam, F.; Ciavatta, M. L.; Carbone, M.; Manzo, E.; Mollo, E.; Gavagnin, M. Biochem. Syst. Ecol.2010, 38, 686–690.
Gavin, N. M.; Durako, M. J. Aquat. Bot.2011, 95(3), 242–247.
Iatrides, M. C.; Artnad, J.; Vicente, N. Oceanol. Acta.1983, 6, 73–77.
Sica, D.; Picialli, V.; Masullo, A. Phytochemistry1984, 23, 2609–2611.
Nichols, P. D.; Johns, R. B. Phytochemistry1985, 24(1), 81–84.
Volkman, J. K.; Gillan, F. T.; Johns, R. B.; Eglinton, G. Geochim. Cosmochim. Acta1981, 45, 1817–1828.
Kawasaki, W.; Matsui, K.; Akakabe, Y.; Itai, N.; Kajiwara, T. Phytochemistry1998, 47, 27–29.
Slusarczyk, S.; Hajnos, M.; Skalicka-Wcznaik, K.; Matkowski, A. Food Chem.2009, 113, 134–138.
Viso, A. C.; Pesando, D.; Bernard, P.; Marty, J. C. Phytochemistry1993, 34, 381–387.
Vaskovsky, V. E.; Khotimchenko, S. V.; Xia, B.; Hefang, L. Phytochemistry1996, 42(5), 1347–1356.
Goncharova, S. N.; Sanina, N. M.; Kostetsky, E. Y. Biochem. Soc. Trans.2000, 28, 887–890.
Sanina, N.; Goncharova, S.; Kostetsky, E. Y. Phytochemistry2004, 65, 721–730.
Sanina, N. M.; Goncharova, S. N.; Kostesky, E. Y. Phytochemistry2008, 69, 1517–1527.
Wink, M. Phytochemistry2003, 64, 3–19.
Khotimchenko, S. V. Phytochemistry1993, 33(2), 369–372.
Waycott, M.; Procaccini, G.; Les, D. H.; Reusch, T. B. H. Seagrasses: Biolgy, Ecology, and Conservation, Springer: Berlin, 2006, p. 25–50.
Sanina, N. M.; Kostetsky, E. Y. Comp. Biochem. Physiol.2002, 133, 143–153.
Sanina, N. M.; Goncharova, S. N.; Kostetsky, E. Y. Advanced Researches of Plant Lipids., Kluwer Academic Publishers, Dordrecht, 2003, p. 385–388.
Harrison, P. G.; Chan, A. T. Mar. Biol.1980, 61, 21–26.
Jensen, P. R.; Jenkins, K. M.; Porter, D.; Fenical, W. Appl. Environ. Microbiol.1998, 64(4), 1490–1496
Bhosale, S. H.; Nagle, V. L.; Jagtap, G. D. Mar. Biotech.2002, 4, 111–118.
Kumar, C. S.; Sarada, D. V. L.; Gideon, T. P.; Rengasamy, R. World J. Microbiol. Biotechnol.2008, 24, 1989–1992.
Kontiza, I.; Stavri, M.; Zloh, M.; Vagias, C.; Gibbons, S.; Roussis, V. Tetrahedron2008, 64, 1696–1702.
Ravikumar, S.; Nanthini devi, K.; Ajithkumar, T. T.; Ajmalkhan, M. Ann. Biol. Res.2011, 2(1), 88–93.
Kannan, R. R. R.; Arumugam, R.; Anantharaman, P. Asian Pacific J. Trop. Med.2010, 11, 890–893.
Kannan, R. R. R.; Arumugam, R.; Anantharaman, P. Food Chem.2012, 135, 2470–2473.
Kannan, R. R. R.; Arumugam, R.; Iyapparaj, P.; Thangaradjou, T.; Anantharaman, P. Food Chem.2013, 136, 1484–1489.
Harrison, P. G. Mar. Biol.1982, 67, 225–230.
Nichols, P. D.; Klumpp, D. W.; Johns, R. B. Phytochemistry1982, 21, 1613–1621.
McMillan, C. Aquat. Bot.1983, 16, 337–347.
Hernandez, M. E.; Mead, R.; Peralba, M. C.; Jaffe, R. Org. Geochem.2001, 32, 21–32.
Preen, A.; Marsh, H. Wildlife Res.1995, 22, 507–519.
Aragones, L. Dugongs and Green turtles: Grazers in the tropical seagrass ecosystem. Ph.D. Thesis, James Cook University, 1996.
Ignat, I.; Volf, I.; Popa, V. I. Food Chem.2011, 126, 1821–1835.
Vergeer, L. H. T; Develi, A. Aquat. Bot.1997, 58, 65–72.
Achamlale, S.; Rezzonica, B.; Dubois, M. G. Food chem.2009, 113, 878–883.
Cariello, L.; Zanetti, L.; De Stefano, S. Comp. Biochem. Physiol. B.1979, 62, 159–611.
McMillan, C. Aquat. Bot.1986, 25, 63–72.
Nuissier, G.; Diaba, F.; Dubois, M. G. Innovative Food Sci. Emerging Tech.2008, 9, 396–400.
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is published with open access at Springerlink.com
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Subhashini, P., Dilipan, E., Thangaradjou, T. et al. Bioactive natural products from marine angiosperms: abundance and functions. Nat. Prod. Bioprospect. 3, 129–136 (2013). https://doi.org/10.1007/s13659-013-0043-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13659-013-0043-6