Abstract
A chemical investigation on the cultures of Xylaria carpophila led to the isolation of one known cyclopeptide cyclo(Nmethyl- l -Phe- l -Pro- l -Leu- d -Ile- l -Val) (1), five new sesquiterpenes, named as xylcarpins A–E (2–6), and another known compound (7). The structures were determined by extensive NMR and MS spectroscopic analysis. The absolute configuration of 1 was established by use of Marfey’s method and ROESY spectroscopic data. All compounds were tested for their cytotoxicities against five human cancer cell lines. Compound 7 showed week inhibitory activity.
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Yin, X., Feng, T., Li, ZH. et al. Chemical investigation on the cultures of the fungus Xylaria carpophila. Nat. Prod. Bioprospect. 1, 75–80 (2011). https://doi.org/10.1007/s13659-011-0011-y
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DOI: https://doi.org/10.1007/s13659-011-0011-y