Abstract
One of the traditional folk medicine in the Malaysia is using porcupine bezoar. It was reported as universal medicine in ancient time. This bezoar has been a myth to the locals. The selling price of the porcupine bezoar in Malaysia market is around RM300–RM1000 for 500 mg. The widespread use of the bezoar as an alternative medicine for treatment of deadly illnesses in Malaysia was passed down from generations of the multi-diverse ethnicity environment that existed here. Additionally, porcupine bezoar was also known as lifesaver and used by patients with terminal illness. Porcupine bezoar was found in the gastrointestinal tract of porcupine and made up of indigestible plant matters. Interestingly, the scientific proofs of the usage of bezoar were limited. The chemical profile and the medicinal properties of the bezoar is still unknown. The main focus of this review paper is on the porcupine bezoar which can be found in Malaysia.
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References
Bao SH (2014) 重镇化痰可治瘟病-箭猪枣非治百病. Guang Ming Daily Newspaper. Retrieved from http://www.guangming.com.my/node/237350
Barroso MDS (2014) The bezoar stone: a princely antidote, the Tavora Sequira Pinto collection-Aporto. Acta med Hist Adriat 12(1):77–98
Brown V (2015) Not a miracle cure. The star online (Newspaper)—behind the cage. Retrieved from https://www.thestar.com.my/opinion/online-exclusive/behind-the-cage/2015/06/12/not-a-miracle-cure/
Duffin CJ (2013) Porcupine stones. Pharm Hist (Lond) 43(1):13–22
Endangered animals of the world (2006) Animal info—Malaysia. Retrieved from http://www.animalinfo.org/country/malaysia.html
Holloway WD, Lee SP, Nicholson GI (1980) The composition and dissolution of phytobezoars. Arch Pathol Lab Med 104:159–161
Khan FAY, Nasir MMH, Jalal T, Razali S, Hassan H, Asuhaimi FA, Wahab RA (2017) In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549—a preliminary study. Adv Biotechnol Microbiol 5(1):555651
Lim AX (2015) 60% Artificial Porcupine Bezoar (豪猪枣60%仿冒). Malaysia Oriental Daily Newspapar. Retrieved from http://www.orientaldaily.com.my/s/74980
Liu XH (2016) The mystery of porcupine bezoar (箭猪枣之迷思). Nanyang Siang Pau. Retrieved from http://www.enanyang.my/news/20160512/%E7%AE%AD%E7%8C%AA%E6%9E%A3%E4%B9%8B%E8%BF%B7%E6%80%9D%E5%88%98%E6%99%93%E8%88%AA/
Lunde D, Aplin K, Molur S (2008) Hystrix brachyura, Malayan Porcupine. The IUCN Red List of Threatened Species. Retrieved from http://www.iucnredlist.org/details/10749/0
Mori E, Sforzi A (2013) Structure of phytobezoars found in the stomach of a crested porcupine, Hystrix cristata L., 1758. Folia Zool 62(3):232–234
The Star Online-Newspaper (2015) Medicine shops claim wildlife products a ‘cure-all’. Retrieved from https://www.thestar.com.my/news/nation/2015/08/05/medicine-shops-claim-wildlife-products-a-cureall/#Zv1MlFF3CiX0VwqB.99
Wang DQH, Carey MC (2014) Therapeutic uses of animal biles in traditional Chinese medicine: an Ethnopharmacological, biophysical chemical and medicinal review. World J Gastroenterol 20(29):9952–9970
Wong LP, AbuBakar S (2013) Health beliefs and practices related to dengue fever: a focus group study. PLOS Negl Trop Dis 7(7):e2310
Yew PN, Lee WL, Lim YY (2017) Antioxidant and intracellular reactive oxygen species/reactive nitrogen species scavenging activities of three porcupine bezoars from Hystrix brachyura. Pharmacogn Res 9(4):366–371
Yew PN, Goh BH, Lim YY, Lee WL (2018) Gastrointestinal bezoar stones: current knowledge and future perspective on the potential of plant-derived phytobezoar in cancer treatment. In: Akhtar MS, Swamy MK (eds) Anticancer plants: natural products and biotechnological implements. Springer, Singapore, pp 19–39
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The manuscript was designed and written by Tan Chu Shan. Ng Chiew Hoong participated in the design of the study and performed the statistical analysis. The materials were collected by Loh Yean Chun. Dr Yam Mun Fei conceived and supervised the whole project. All authors read and approved the final manuscript.
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Tan, C.S., Ng, C.H., Loh, Y.C. et al. A traditional folk medicine in Malaysia: porcupine bezoar. Orient Pharm Exp Med 19, 131–136 (2019). https://doi.org/10.1007/s13596-019-00370-4
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DOI: https://doi.org/10.1007/s13596-019-00370-4