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New aliphatic ester constituents of Hygrophila auriculata (K. Schum) Heine from the Koshi river basin

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Abstract

This research is meant for the isolation of the compounds out from the methanolic extract of the Hygrophila auriculata. This herb was customarily used as a diuretic to cure the inflammation, pain, urinal infections, and the gout. To isolate the compounds from methanolic extract of Hygrophila auriculata which was taken from Bihar’s Koshi river belt, open silica gel column chromatographic methods with different solvent mixtures were applied. The elucidation of the structure of the different separated phytoconstituent was accomplished through spectral data analysis, chemical reactions and their literary comparisons. Phytochemical analysis of methanolic extract of Hygrophila auriculata gave a new compound identified as n-octa-triacontan-3-one-19α, 31α-diol (4) and along with the four known aliphatic ester compounds n-hexacos-21-one-1-ol (1), trans-tetracont-7-en-1-ol (2), n–octacosan-8-one (3) and n-heptacosan-11α-ol (5). A new compound was found with four other known compounds as aliphatic esters from H. auriculata extract.

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Acknowledgements

Authors are jointly thankful from the bottom of their hearts to Honorable Vice Chancellor, Integral University, for providing necessary facilities in university premises for this research. We also would like to extent our sincere thanks to Prof. (Dr.) Anjani Kumar Sinha, the Principal of M L T Saharsa College, Saharsa, Bihar, INDIA for his supports of various kinds particularly for giving authenticated samples of Hygrophila auriculata.

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Authors and Affiliations

  1. Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Misurata University, Misurata, Libya

    Md. Sarfaraj Hussain & Hesham Mustafa Gebira

  2. Faculty of Pharmacy, Integral University, Kursi Road, Dasauli, Lucknow, India

    Md. Sarfaraj Hussain

  3. Pharmaceutical Technical Department, Faculty of Medical Technology, Misurata University, Misurata, Libya

    Hend Ismail

  4. Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, New Delhi, India

    Mohammed Ali

Authors
  1. Md. Sarfaraj Hussain
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  2. Hesham Mustafa Gebira
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  3. Hend Ismail
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  4. Mohammed Ali
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Correspondence to Md. Sarfaraj Hussain.

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This manuscript described has not been published before; not under consideration for publication anywhere else; and has been approved by all co-authors.

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Hussain, M.S., Gebira, H.M., Ismail, H. et al. New aliphatic ester constituents of Hygrophila auriculata (K. Schum) Heine from the Koshi river basin. Orient Pharm Exp Med 19, 251–258 (2019). https://doi.org/10.1007/s13596-018-0336-8

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  • DOI: https://doi.org/10.1007/s13596-018-0336-8

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