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Correction to: Human Cell (2020) 33:709–720 https://doi.org/10.1007/s13577-020-00353-7
In the original publication of the article, Fig. 1 and Fig. 3 were published with errors. The correct Fig. 1 and 3 are given in this correction.
Overexpression of RCC2 is correlated with histological malignancy and chemotherapy resistance in epatocellular carcinoma (HCC) tissues. a RCC2 expression examined by immunohistochemical staining in different grades of HCC tissues. (IHC, × 200). b RCC2 protein levels in normal and HCC liver tissues (*p < 0.05, **p < 0.01, ***p < 0.001 compared with normal liver tissues). n = 5 for normal and 6 for others. c RCC2 expression in DDP-sensitive and DDP-resistant HCC tissue and their matched para-cancerous tissues were detected by immunohistochemical analysis. (IHC, × 200). d RCC2 protein expression levels in DDP-sensitive and DDP-resistant HCC tissue and their matched para-cancerous tissues were detected by western blot analysis. (**p < 0.01, ***p < 0.001). n = 4, 5, 4, 6 for each group (1–4). e RCC2 mRNA expression levels in DDP-sensitive and DDP-resistant HCC tissue in HCC tissues were detected by qPCR. n = 17/12. Data are presented as the mean ± SEM. Difference between two groups was analyzed by Student’s two-tail t test. Difference among three or more groups was compared by ANOVA with Tukey’s post hoc analysis
Effects of RCC2 expression on biological behaviors of HCC cells in vitro. a The silencing effect of shRNA1-RCC2 and shRNA2-RCC2 was confirmed by western blot in Huh7 and HepG2 cells. b Colony formation assay results showed that silencing of RCC2 significantly decreased the number of colonies of Huh7 and HepG2 cells compared to the SC groups. The knockdown of RCC2 expression could significantly inhibit c migration and d invasion of HCC cells. Magnification 200 ×. **p < 0.01, ***p < 0.001 compared with SC-shRNA group. Data are presented as the mean ± SEM. Differences among groups were compared by ANOVA with Tukey’s post-hoc analysis
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Chen, Q., Jiang, P., Jia, B. et al. Correction to: RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma. Human Cell 34, 706–710 (2021). https://doi.org/10.1007/s13577-020-00480-1
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DOI: https://doi.org/10.1007/s13577-020-00480-1